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Molecular Mechanisms and Cellular Pathways Implicated in Machado-Joseph Disease Pathogenesis.
Adv Exp Med Biol. 2018;1049:349-367. doi: 10.1007/978-3-319-71779-1_18.
Adv Exp Med Biol. 2018.
PMID: 29427113
Review.
Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado-Joseph disease.
Duarte-Neves J, Gonçalves N, Cunha-Santos J, Simões AT, den Dunnen WF, Hirai H, Kügler S, Cavadas C, Pereira de Almeida L.
Duarte-Neves J, et al.
Hum Mol Genet. 2015 Oct 1;24(19):5451-63. doi: 10.1093/hmg/ddv271. Epub 2015 Jul 27.
Hum Mol Genet. 2015.
PMID: 26220979
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Caloric restriction blocks neuropathology and motor deficits in Machado-Joseph disease mouse models through SIRT1 pathway.
Cunha-Santos J, Duarte-Neves J, Carmona V, Guarente L, Pereira de Almeida L, Cavadas C.
Cunha-Santos J, et al. Among authors: duarte neves j.
Nat Commun. 2016 May 11;7:11445. doi: 10.1038/ncomms11445.
Nat Commun. 2016.
PMID: 27165717
Free PMC article.
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Neuropeptide Y (NPY) intranasal delivery alleviates Machado-Joseph disease.
Duarte-Neves J, Cavadas C, Pereira de Almeida L.
Duarte-Neves J, et al.
Sci Rep. 2021 Feb 8;11(1):3345. doi: 10.1038/s41598-021-82339-5.
Sci Rep. 2021.
PMID: 33558582
Free PMC article.
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Identification of the calpain-generated toxic fragment of ataxin-3 protein provides new avenues for therapy of Machado-Joseph disease| Spinocerebellar ataxia type 3.
Simões AT, Carmona V, Duarte-Neves J, Cunha-Santos J, Pereira de Almeida L.
Simões AT, et al. Among authors: duarte neves j.
Neuropathol Appl Neurobiol. 2022 Feb;48(1):e12748. doi: 10.1111/nan.12748. Epub 2021 Aug 23.
Neuropathol Appl Neurobiol. 2022.
PMID: 34273111
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Neuropeptide Y (NPY) as a therapeutic target for neurodegenerative diseases.
Duarte-Neves J, Pereira de Almeida L, Cavadas C.
Duarte-Neves J, et al.
Neurobiol Dis. 2016 Nov;95:210-24. doi: 10.1016/j.nbd.2016.07.022. Epub 2016 Jul 25.
Neurobiol Dis. 2016.
PMID: 27461050
Review.
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