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Page 1
Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates.
Dias Viegas FP, de Freitas Silva M, Divino da Rocha M, Castelli MR, Riquiel MM, Machado RP, Vaz SM, Simões de Lima LM, Mancini KC, Marques de Oliveira PC, Morais ÉP, Gontijo VS, da Silva FMR, D'Alincourt da Fonseca Peçanha D, Castro NG, Neves GA, Giusti-Paiva A, Vilela FC, Orlandi L, Camps I, Veloso MP, Leomil Coelho LF, Ionta M, Ferreira-Silva GÁ, Pereira RM, Dardenne LE, Guedes IA, de Oliveira Carneiro Junior W, Quaglio Bellozi PM, Pinheiro de Oliveira AC, Ferreira FF, Pruccoli L, Tarozzi A, Viegas C Jr. Dias Viegas FP, et al. Among authors: da silva fmr. Eur J Med Chem. 2018 Mar 10;147:48-65. doi: 10.1016/j.ejmech.2018.01.066. Epub 2018 Jan 31. Eur J Med Chem. 2018. PMID: 29421570
Cardanol-derived AChE inhibitors: Towards the development of dual binding derivatives for Alzheimer's disease.
Lemes LFN, de Andrade Ramos G, de Oliveira AS, da Silva FMR, de Castro Couto G, da Silva Boni M, Guimarães MJR, Souza INO, Bartolini M, Andrisano V, do Nascimento Nogueira PC, Silveira ER, Brand GD, Soukup O, Korábečný J, Romeiro NC, Castro NG, Bolognesi ML, Romeiro LAS. Lemes LFN, et al. Among authors: da silva fmr. Eur J Med Chem. 2016 Jan 27;108:687-700. doi: 10.1016/j.ejmech.2015.12.024. Epub 2015 Dec 17. Eur J Med Chem. 2016. PMID: 26735910
Environmental implications of combustion of rice husk at high temperatures and for an extended period for energy generation.
Brandalise JN, Guidoni LLC, Martins GA, Lopes ER, Nardino M, Bobrowski VL, Nadaleti WC, da Silva FMR Jr, Lucia T Jr, Corrêa ÉK. Brandalise JN, et al. Among authors: da silva fmr jr. Environ Sci Pollut Res Int. 2023 Oct;30(46):102222-102230. doi: 10.1007/s11356-023-29588-1. Epub 2023 Sep 4. Environ Sci Pollut Res Int. 2023. PMID: 37667116
Design, synthesis, and biological evaluation of new thalidomide-donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation.
Cristancho Ortiz CJ, de Freitas Silva M, Pruccoli L, Fonseca Nadur N, de Azevedo LL, Kümmerle AE, Guedes IA, Dardenne LE, Leomil Coelho LF, Guimarães MJ, da Silva FMR, Castro N, Gontijo VS, Rojas VCT, de Oliveira MK, Vilela FC, Giusti-Paiva A, Barbosa G, Lima LM, Pinheiro GB, Veras LG, Mortari MR, Tarozzi A, Viegas C Jr. Cristancho Ortiz CJ, et al. Among authors: da silva fmr. RSC Med Chem. 2022 Mar 17;13(5):568-584. doi: 10.1039/d1md00374g. eCollection 2022 May 25. RSC Med Chem. 2022. PMID: 35694691 Free PMC article.
Genetic damage in coal and uranium miners.
da Silva FMR Júnior, Tavella RA, Fernandes CLF, Dos Santos M. da Silva FMR Júnior, et al. Mutat Res Genet Toxicol Environ Mutagen. 2021 Jun;866:503348. doi: 10.1016/j.mrgentox.2021.503348. Epub 2021 Mar 16. Mutat Res Genet Toxicol Environ Mutagen. 2021. PMID: 33985692 Free article. Review.
Design, synthesis and evaluation of novel feruloyl-donepezil hybrids as potential multitarget drugs for the treatment of Alzheimer's disease.
Dias KS, de Paula CT, Dos Santos T, Souza IN, Boni MS, Guimarães MJ, da Silva FM, Castro NG, Neves GA, Veloso CC, Coelho MM, de Melo IS, Giusti FC, Giusti-Paiva A, da Silva ML, Dardenne LE, Guedes IA, Pruccoli L, Morroni F, Tarozzi A, Viegas C Jr. Dias KS, et al. Eur J Med Chem. 2017 Apr 21;130:440-457. doi: 10.1016/j.ejmech.2017.02.043. Epub 2017 Feb 21. Eur J Med Chem. 2017. PMID: 28282613
17 results