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Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates.
Eur J Med Chem. 2018 Mar 10;147:48-65. doi: 10.1016/j.ejmech.2018.01.066. Epub 2018 Jan 31.
Eur J Med Chem. 2018.
PMID: 29421570
Donepezil: an important prototype to the design of new drug candidates for Alzheimer's disease.
Rodrigues Simões MC, Dias Viegas FP, Moreira MS, de Freitas Silva M, Riquiel MM, da Rosa PM, Castelli MR, dos Santos MH, Soares MG, Viegas C Jr.
Rodrigues Simões MC, et al. Among authors: riquiel mm.
Mini Rev Med Chem. 2014 Jan;14(1):2-19. doi: 10.2174/1389557513666131119201353.
Mini Rev Med Chem. 2014.
PMID: 24251806
Review.
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New multifunctional AChE inhibitor drug prototypes protect against Aβ-induced memory deficit.
Bellozi PMQ, Campos AC, Viegas FPD, Silva MF, Machado RP, Vaz SM, Riquiel MM, Carneiro-Junior WO, Lima IVA, Saliba SW, Vaz GN, Viegas C Jr, de Oliveira ACP.
Bellozi PMQ, et al. Among authors: riquiel mm.
Neurol Sci. 2020 Feb;41(2):451-455. doi: 10.1007/s10072-019-04036-6. Epub 2019 Sep 11.
Neurol Sci. 2020.
PMID: 31506829
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