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Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates.
Dias Viegas FP, de Freitas Silva M, Divino da Rocha M, Castelli MR, Riquiel MM, Machado RP, Vaz SM, Simões de Lima LM, Mancini KC, Marques de Oliveira PC, Morais ÉP, Gontijo VS, da Silva FMR, D'Alincourt da Fonseca Peçanha D, Castro NG, Neves GA, Giusti-Paiva A, Vilela FC, Orlandi L, Camps I, Veloso MP, Leomil Coelho LF, Ionta M, Ferreira-Silva GÁ, Pereira RM, Dardenne LE, Guedes IA, de Oliveira Carneiro Junior W, Quaglio Bellozi PM, Pinheiro de Oliveira AC, Ferreira FF, Pruccoli L, Tarozzi A, Viegas C Jr. Dias Viegas FP, et al. Among authors: gontijo vs. Eur J Med Chem. 2018 Mar 10;147:48-65. doi: 10.1016/j.ejmech.2018.01.066. Epub 2018 Jan 31. Eur J Med Chem. 2018. PMID: 29421570
Inhibition of cysteine proteases by a natural biflavone: behavioral evaluation of fukugetin as papain and cruzain inhibitor.
Assis DM, Gontijo VS, de Oliveira Pereira I, Santos JA, Camps I, Nagem TJ, Ellena J, Izidoro MA, dos Santos Tersariol IL, de Barros NM, Doriguetto AC, dos Santos MH, Juliano MA. Assis DM, et al. Among authors: gontijo vs. J Enzyme Inhib Med Chem. 2013 Aug;28(4):661-70. doi: 10.3109/14756366.2012.668539. Epub 2012 Apr 2. J Enzyme Inhib Med Chem. 2013. PMID: 22468751
Leishmanicidal, antiproteolytic and antioxidant evaluation of natural biflavonoids isolated from Garcinia brasiliensis and their semisynthetic derivatives.
Gontijo VS, Judice WA, Codonho B, Pereira IO, Assis DM, Januário JP, Caroselli EE, Juliano MA, de Carvalho Dosatti A, Marques MJ, Viegas Junior C, Henrique dos Santos M. Gontijo VS, et al. Eur J Med Chem. 2012 Dec;58:613-23. doi: 10.1016/j.ejmech.2012.06.021. Epub 2012 Jun 28. Eur J Med Chem. 2012. PMID: 23178961
Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer's Disease.
de Freitas Silva M, Tardelli Lima E, Pruccoli L, Castro NG, Guimarães MJR, M R da Silva F, Fonseca Nadur N, de Azevedo LL, Kümmerle AE, Guedes IA, Dardenne LE, Gontijo VS, Tarozzi A, Viegas C. de Freitas Silva M, et al. Among authors: gontijo vs. Molecules. 2020 Jul 10;25(14):3165. doi: 10.3390/molecules25143165. Molecules. 2020. PMID: 32664425 Free PMC article.
20 results