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Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates.
Eur J Med Chem. 2018 Mar 10;147:48-65. doi: 10.1016/j.ejmech.2018.01.066. Epub 2018 Jan 31.
Eur J Med Chem. 2018.
PMID: 29421570
Donepezil: an important prototype to the design of new drug candidates for Alzheimer's disease.
Rodrigues Simões MC, Dias Viegas FP, Moreira MS, de Freitas Silva M, Riquiel MM, da Rosa PM, Castelli MR, dos Santos MH, Soares MG, Viegas C Jr.
Rodrigues Simões MC, et al. Among authors: dias viegas fp.
Mini Rev Med Chem. 2014 Jan;14(1):2-19. doi: 10.2174/1389557513666131119201353.
Mini Rev Med Chem. 2014.
PMID: 24251806
Review.
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3-Hydroxy-piperidinyl-N-benzyl-acyl-arylhydrazone derivatives reduce neuropathic pain and increase thermal threshold mediated by opioid system.
Dos Santos NM, Pereira NC, de Albuquerque APS, Dias Viegas FP, Veloso C, Vilela FC, Giusti-Paiva A, da Silva ML, da Silva JRT, Viegas C Jr.
Dos Santos NM, et al. Among authors: dias viegas fp.
Biomed Pharmacother. 2018 Mar;99:492-498. doi: 10.1016/j.biopha.2018.01.077. Epub 2018 Feb 20.
Biomed Pharmacother. 2018.
PMID: 29665651
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Alzheimer's Disease: Related Targets, Synthesis of Available Drugs, Bioactive Compounds Under Development and Promising Results Obtained from Multi-target Approaches.
Pirolla NFF, Batista VS, Dias Viegas FP, Gontijo VS, McCarthy CR, Viegas C, Nascimento-Júnior NM.
Pirolla NFF, et al. Among authors: dias viegas fp.
Curr Drug Targets. 2021;22(5):505-538. doi: 10.2174/1389450121999200819144544.
Curr Drug Targets. 2021.
PMID: 32814524
Review.
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Antinociceptive Effect of Dillenia indica (Linn.) Mediated by Opioid and Cannabinoid Systems: Pharmacological and Chemical Studies.
de Souza AA, Dias Viegas FP, Gontijo VS, Vieira Domingues JS, Giusti-Paiva A, Vilela FC, da Silva GA, Amaral JG, Lopes NP, Viegas C Jr.
de Souza AA, et al. Among authors: dias viegas fp.
Chem Biodivers. 2024 Mar;21(3):e202301508. doi: 10.1002/cbdv.202301508. Epub 2024 Mar 1.
Chem Biodivers. 2024.
PMID: 38092696
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