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Simultaneous downregulation of KLF5 and Fli1 is a key feature underlying systemic sclerosis.
Noda S, Asano Y, Nishimura S, Taniguchi T, Fujiu K, Manabe I, Nakamura K, Yamashita T, Saigusa R, Akamata K, Takahashi T, Ichimura Y, Toyama T, Tsuruta D, Trojanowska M, Nagai R, Sato S. Noda S, et al. Among authors: yamashita t. Nat Commun. 2014 Dec 12;5:5797. doi: 10.1038/ncomms6797. Nat Commun. 2014. PMID: 25504335 Free PMC article.
Increased expression of chemerin in endothelial cells due to Fli1 deficiency may contribute to the development of digital ulcers in systemic sclerosis.
Akamata K, Asano Y, Taniguchi T, Yamashita T, Saigusa R, Nakamura K, Noda S, Aozasa N, Toyama T, Takahashi T, Ichimura Y, Sumida H, Tada Y, Sugaya M, Kadono T, Sato S. Akamata K, et al. Among authors: yamashita t. Rheumatology (Oxford). 2015 Jul;54(7):1308-16. doi: 10.1093/rheumatology/keu479. Epub 2014 Dec 23. Rheumatology (Oxford). 2015. PMID: 25539827
Multifaceted contribution of the TLR4-activated IRF5 transcription factor in systemic sclerosis.
Saigusa R, Asano Y, Taniguchi T, Yamashita T, Ichimura Y, Takahashi T, Toyama T, Yoshizaki A, Sugawara K, Tsuruta D, Taniguchi T, Sato S. Saigusa R, et al. Among authors: yamashita t. Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15136-41. doi: 10.1073/pnas.1520997112. Epub 2015 Nov 23. Proc Natl Acad Sci U S A. 2015. PMID: 26598674 Free PMC article.
The impact of transcription factor Fli1 deficiency on the regulation of angiogenesis.
Toyama T, Asano Y, Miyagawa T, Nakamura K, Hirabayashi M, Yamashita T, Saigusa R, Miura S, Ichimura Y, Takahashi T, Taniguchi T, Yoshizaki A, Sato S. Toyama T, et al. Among authors: yamashita t. Exp Dermatol. 2017 Oct;26(10):912-918. doi: 10.1111/exd.13341. Epub 2017 Jul 10. Exp Dermatol. 2017. PMID: 28370536
6,790 results