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SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice.
Vallon V, Gerasimova M, Rose MA, Masuda T, Satriano J, Mayoux E, Koepsell H, Thomson SC, Rieg T. Vallon V, et al. Among authors: koepsell h. Am J Physiol Renal Physiol. 2014 Jan;306(2):F194-204. doi: 10.1152/ajprenal.00520.2013. Epub 2013 Nov 13. Am J Physiol Renal Physiol. 2014. PMID: 24226524 Free PMC article.
Distribution of organic anion transporters NaDC3 and OAT1-3 along the human nephron.
Breljak D, Ljubojević M, Hagos Y, Micek V, Balen Eror D, Vrhovac Madunić I, Brzica H, Karaica D, Radović N, Kraus O, Anzai N, Koepsell H, Burckhardt G, Burckhardt BC, Sabolić I. Breljak D, et al. Among authors: koepsell h. Am J Physiol Renal Physiol. 2016 Jul 1;311(1):F227-38. doi: 10.1152/ajprenal.00113.2016. Epub 2016 Apr 6. Am J Physiol Renal Physiol. 2016. PMID: 27053689 Free article.
Unmasking a sustained negative effect of SGLT2 inhibition on body fluid volume in the rat.
Masuda T, Watanabe Y, Fukuda K, Watanabe M, Onishi A, Ohara K, Imai T, Koepsell H, Muto S, Vallon V, Nagata D. Masuda T, et al. Among authors: koepsell h. Am J Physiol Renal Physiol. 2018 Sep 1;315(3):F653-F664. doi: 10.1152/ajprenal.00143.2018. Epub 2018 May 23. Am J Physiol Renal Physiol. 2018. PMID: 29790389 Free PMC article.
SGLT2 inhibition and renal urate excretion: role of luminal glucose, GLUT9, and URAT1.
Novikov A, Fu Y, Huang W, Freeman B, Patel R, van Ginkel C, Koepsell H, Busslinger M, Onishi A, Nespoux J, Vallon V. Novikov A, et al. Among authors: koepsell h. Am J Physiol Renal Physiol. 2019 Jan 1;316(1):F173-F185. doi: 10.1152/ajprenal.00462.2018. Epub 2018 Nov 14. Am J Physiol Renal Physiol. 2019. PMID: 30427222 Free PMC article.
Gene deletion of the Na+-glucose cotransporter SGLT1 ameliorates kidney recovery in a murine model of acute kidney injury induced by ischemia-reperfusion.
Nespoux J, Patel R, Hudkins KL, Huang W, Freeman B, Kim YC, Koepsell H, Alpers CE, Vallon V. Nespoux J, et al. Among authors: koepsell h. Am J Physiol Renal Physiol. 2019 Jun 1;316(6):F1201-F1210. doi: 10.1152/ajprenal.00111.2019. Epub 2019 Apr 17. Am J Physiol Renal Physiol. 2019. PMID: 30995111 Free PMC article.
Knockout of Na+-glucose cotransporter SGLT1 mitigates diabetes-induced upregulation of nitric oxide synthase NOS1 in the macula densa and glomerular hyperfiltration.
Song P, Huang W, Onishi A, Patel R, Kim YC, van Ginkel C, Fu Y, Freeman B, Koepsell H, Thomson S, Liu R, Vallon V. Song P, et al. Among authors: koepsell h. Am J Physiol Renal Physiol. 2019 Jul 1;317(1):F207-F217. doi: 10.1152/ajprenal.00120.2019. Epub 2019 May 15. Am J Physiol Renal Physiol. 2019. PMID: 31091127 Free PMC article.
Revised immunolocalization of the Na+-D-glucose cotransporter SGLT1 in rat organs with an improved antibody.
Balen D, Ljubojevic M, Breljak D, Brzica H, Zlender V, Koepsell H, Sabolic I. Balen D, et al. Among authors: koepsell h. Am J Physiol Cell Physiol. 2008 Aug;295(2):C475-89. doi: 10.1152/ajpcell.00180.2008. Epub 2008 Jun 4. Am J Physiol Cell Physiol. 2008. PMID: 18524944 Free article.
Previously, we characterized localization of Na(+)-glucose cotransporter SGLT1 (Slc5a1) in the rat kidney using a polyclonal antibody against the synthetic COOH-terminal peptide of the rat protein (Sabolic I, Skarica M, Gorboulev V, Ljubojevic M, Balen D, Herak-Kramberger CM, …
Previously, we characterized localization of Na(+)-glucose cotransporter SGLT1 (Slc5a1) in the rat kidney using a polyclonal antibody agains …
245 results