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Translational control of ERK signaling through miRNA/4EHP-directed silencing.
Jafarnejad SM, Chapat C, Matta-Camacho E, Gelbart IA, Hesketh GG, Arguello M, Garzia A, Kim SH, Attig J, Shapiro M, Morita M, Khoutorsky A, Alain T, Gkogkas CG, Stern-Ginossar N, Tuschl T, Gingras AC, Duchaine TF, Sonenberg N. Jafarnejad SM, et al. Among authors: alain t. Elife. 2018 Feb 7;7:e35034. doi: 10.7554/eLife.35034. Elife. 2018. PMID: 29412140 Free PMC article.
p53-dependent translational control of senescence and transformation via 4E-BPs.
Petroulakis E, Parsyan A, Dowling RJ, LeBacquer O, Martineau Y, Bidinosti M, Larsson O, Alain T, Rong L, Mamane Y, Paquet M, Furic L, Topisirovic I, Shahbazian D, Livingstone M, Costa-Mattioli M, Teodoro JG, Sonenberg N. Petroulakis E, et al. Among authors: alain t. Cancer Cell. 2009 Nov 6;16(5):439-46. doi: 10.1016/j.ccr.2009.09.025. Cancer Cell. 2009. PMID: 19878875 Free article.
The helicase protein DHX29 promotes translation initiation, cell proliferation, and tumorigenesis.
Parsyan A, Shahbazian D, Martineau Y, Petroulakis E, Alain T, Larsson O, Mathonnet G, Tettweiler G, Hellen CU, Pestova TV, Svitkin YV, Sonenberg N. Parsyan A, et al. Among authors: alain t. Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22217-22. doi: 10.1073/pnas.0909773106. Epub 2009 Dec 11. Proc Natl Acad Sci U S A. 2009. PMID: 20018725 Free PMC article.
mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs.
Dowling RJ, Topisirovic I, Alain T, Bidinosti M, Fonseca BD, Petroulakis E, Wang X, Larsson O, Selvaraj A, Liu Y, Kozma SC, Thomas G, Sonenberg N. Dowling RJ, et al. Among authors: alain t. Science. 2010 May 28;328(5982):1172-6. doi: 10.1126/science.1187532. Science. 2010. PMID: 20508131 Free PMC article.
Translational control of the activation of transcription factor NF-κB and production of type I interferon by phosphorylation of the translation factor eIF4E.
Herdy B, Jaramillo M, Svitkin YV, Rosenfeld AB, Kobayashi M, Walsh D, Alain T, Sean P, Robichaud N, Topisirovic I, Furic L, Dowling RJO, Sylvestre A, Rong L, Colina R, Costa-Mattioli M, Fritz JH, Olivier M, Brown E, Mohr I, Sonenberg N. Herdy B, et al. Among authors: alain t. Nat Immunol. 2012 Apr 29;13(6):543-550. doi: 10.1038/ni.2291. Nat Immunol. 2012. PMID: 22544393 Free PMC article.
Distinct perturbation of the translatome by the antidiabetic drug metformin.
Larsson O, Morita M, Topisirovic I, Alain T, Blouin MJ, Pollak M, Sonenberg N. Larsson O, et al. Among authors: alain t. Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):8977-82. doi: 10.1073/pnas.1201689109. Epub 2012 May 18. Proc Natl Acad Sci U S A. 2012. PMID: 22611195 Free PMC article.
112 results