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Methionine oxidized apolipoprotein A-I at the crossroads of HDL biogenesis and amyloid formation.
Witkowski A, Chan GKL, Boatz JC, Li NJ, Inoue AP, Wong JC, van der Wel PCA, Cavigiolio G. Witkowski A, et al. FASEB J. 2018 Jun;32(6):3149-3165. doi: 10.1096/fj.201701127R. Epub 2018 Jan 17. FASEB J. 2018. PMID: 29401604 Free PMC article.
Apolipoprotein A-I (apoA-I) shares with other exchangeable apolipoproteins a high level of structural plasticity. ...Our results suggest that even partial Met oxidation of apoA-I can nucleate amyloidogenesis, thus sequestering and inactivating otherwise antiatheroge …
Apolipoprotein A-I (apoA-I) shares with other exchangeable apolipoproteins a high level of structural plasticity. ...Our resul …
Aberrant hetero-disulfide bond formation by the hypertriglyceridemia-associated p.Gly185Cys APOA5 variant (rs2075291).
Sharma V, Witkowski A, Witkowska HE, Dykstra A, Simonsen JB, Nelbach L, Beckstead JA, Pullinger CR, Kane JP, Malloy MJ, Watson G, Forte TM, Ryan RO. Sharma V, et al. Among authors: witkowski a. Arterioscler Thromb Vasc Biol. 2014 Oct;34(10):2254-60. doi: 10.1161/ATVBAHA.114.304027. Epub 2014 Aug 14. Arterioscler Thromb Vasc Biol. 2014. PMID: 25127531 Free PMC article.
718 results