Kuppusamy P - Search Results

1

The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 protein to transcriptionally active wildtype p53.

Madan E, Parker TM, Bauer MR, Dhiman A, Pelham CJ, Nagane M, Kuppusamy ML, Holmes M, Holmes TR, Shaik K, Shee K, Kiparoidze S, Smith SD, Park YA, Gomm JJ, Jones LJ, Tomás AR, Cunha AC, Selvendiran K, Hansen LA, Fersht AR, Hideg K, Gogna R, Kuppusamy P. Madan E, et al. Among authors: kuppusamy ml, kuppusamy p. J Biol Chem. 2018 Mar 23;293(12):4262-4276. doi: 10.1074/jbc.RA117.000950. Epub 2018 Jan 30. J Biol Chem. 2018. PMID: 29382728 Free PMC article.

2

Structure-activity studies on the protection of Trimetazidine derivatives modified with nitroxides and their precursors from myocardial ischemia-reperfusion injury.

Kálai T, Khan M, Balog M, Kutala VK, Kuppusamy P, Hideg K. Kálai T, et al. Among authors: kuppusamy p. Bioorg Med Chem. 2006 Aug 15;14(16):5510-6. doi: 10.1016/j.bmc.2006.04.040. Epub 2006 May 12. Bioorg Med Chem. 2006. PMID: 16697647

3

Curcumin induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by modulating Akt and p38 MAPK.

Weir NM, Selvendiran K, Kutala VK, Tong L, Vishwanath S, Rajaram M, Tridandapani S, Anant S, Kuppusamy P. Weir NM, et al. Among authors: kuppusamy p. Cancer Biol Ther. 2007 Feb;6(2):178-84. doi: 10.4161/cbt.6.2.3577. Epub 2007 Feb 5. Cancer Biol Ther. 2007. PMID: 17218783 Free PMC article.

4

Mercury activates vascular endothelial cell phospholipase D through thiols and oxidative stress.

Hagele TJ, Mazerik JN, Gregory A, Kaufman B, Magalang U, Kuppusamy ML, Marsh CB, Kuppusamy P, Parinandi NL. Hagele TJ, et al. Among authors: kuppusamy ml, kuppusamy p. Int J Toxicol. 2007 Jan-Feb;26(1):57-69. doi: 10.1080/10915810601120509. Int J Toxicol. 2007. PMID: 17365148

5

Skeletal myoblasts transplanted in the ischemic myocardium enhance in situ oxygenation and recovery of contractile function.

Khan M, Kutala VK, Vikram DS, Wisel S, Chacko SM, Kuppusamy ML, Mohan IK, Zweier JL, Kwiatkowski P, Kuppusamy P. Khan M, et al. Among authors: kuppusamy ml, kuppusamy p. Am J Physiol Heart Circ Physiol. 2007 Oct;293(4):H2129-39. doi: 10.1152/ajpheart.00677.2007. Epub 2007 Jul 27. Am J Physiol Heart Circ Physiol. 2007. PMID: 17660391 Free PMC article.

6

EF24 induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by increasing PTEN expression.

Selvendiran K, Tong L, Vishwanath S, Bratasz A, Trigg NJ, Kutala VK, Hideg K, Kuppusamy P. Selvendiran K, et al. Among authors: kuppusamy p. J Biol Chem. 2007 Sep 28;282(39):28609-28618. doi: 10.1074/jbc.M703796200. Epub 2007 Aug 7. J Biol Chem. 2007. PMID: 17684018 Free PMC article.

7

Phospholipase A2 activation regulates cytotoxicity of methylmercury in vascular endothelial cells.

Mazerik JN, Hagele T, Sherwani S, Ciapala V, Butler S, Kuppusamy ML, Hunter M, Kuppusamy P, Marsh CB, Parinandi NL. Mazerik JN, et al. Among authors: kuppusamy ml, kuppusamy p. Int J Toxicol. 2007 Nov-Dec;26(6):553-69. doi: 10.1080/10915810701707759. Int J Toxicol. 2007. PMID: 18066971

8

NCX-4016, a nitro-derivative of aspirin, inhibits EGFR and STAT3 signaling and modulates Bcl-2 proteins in cisplatin-resistant human ovarian cancer cells and xenografts.

Selvendiran K, Bratasz A, Tong L, Ignarro LJ, Kuppusamy P. Selvendiran K, et al. Among authors: kuppusamy p. Cell Cycle. 2008 Jan 1;7(1):81-8. doi: 10.4161/cc.7.1.5103. Epub 2007 Sep 28. Cell Cycle. 2008. PMID: 18196976 Free PMC article.

9

Measurement of oxygenation at the site of stem cell therapy in a murine model of myocardial infarction.

Khan M, Kutala VK, Wisel S, Chacko SM, Kuppusamy ML, Kwiatkowski P, Kuppusamy P. Khan M, et al. Among authors: kuppusamy ml, kuppusamy p. Adv Exp Med Biol. 2008;614:45-52. doi: 10.1007/978-0-387-74911-2_6. Adv Exp Med Biol. 2008. PMID: 18290313

10

NCX-4040, a nitric oxide-releasing aspirin, sensitizes drug-resistant human ovarian xenograft tumors to cisplatin by depletion of cellular thiols.

Bratasz A, Selvendiran K, Wasowicz T, Bobko A, Khramtsov VV, Ignarro LJ, Kuppusamy P. Bratasz A, et al. Among authors: kuppusamy p. J Transl Med. 2008 Feb 26;6:9. doi: 10.1186/1479-5876-6-9. J Transl Med. 2008. PMID: 18302761 Free PMC article.

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