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The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 protein to transcriptionally active wildtype p53.
Madan E, Parker TM, Bauer MR, Dhiman A, Pelham CJ, Nagane M, Kuppusamy ML, Holmes M, Holmes TR, Shaik K, Shee K, Kiparoidze S, Smith SD, Park YA, Gomm JJ, Jones LJ, Tomás AR, Cunha AC, Selvendiran K, Hansen LA, Fersht AR, Hideg K, Gogna R, Kuppusamy P. Madan E, et al. Among authors: holmes m, holmes tr. J Biol Chem. 2018 Mar 23;293(12):4262-4276. doi: 10.1074/jbc.RA117.000950. Epub 2018 Jan 30. J Biol Chem. 2018. PMID: 29382728 Free PMC article.
Droughts impede water balance recovery from fires in the Western United States.
Ahmad SK, Holmes TR, Kumar SV, Lahmers TM, Liu PW, Nie W, Getirana A, Orland E, Bindlish R, Guzman A, Hain CR, Melton FS, Locke KA, Yang Y. Ahmad SK, et al. Among authors: holmes tr. Nat Ecol Evol. 2024 Feb;8(2):229-238. doi: 10.1038/s41559-023-02266-8. Epub 2024 Jan 2. Nat Ecol Evol. 2024. PMID: 38168941
Safety and Performance of the Micra VR Leadless Pacemaker in a Japanese Cohort　- Comparison With Global Studies.
Ando K, Inoue K, Harada T, Shizuta S, Yoshida Y, Kusano K, Onuki T, Watari Y, Fukui A, Sasaki S, Shoda M, Nishii N, Shiose A, Hosoda J, Okai C, Stromberg K, Murphy J, Holmes TR, Soejima K. Ando K, et al. Among authors: holmes tr. Circ J. 2023 Nov 24;87(12):1809-1816. doi: 10.1253/circj.CJ-23-0269. Epub 2023 Aug 2. Circ J. 2023. PMID: 37532552 Free article.
214 results