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Models of retinal diseases and their applicability in drug discovery.
Malek G, Busik J, Grant MB, Choudhary M. Malek G, et al. Among authors: busik j. Expert Opin Drug Discov. 2018 Apr;13(4):359-377. doi: 10.1080/17460441.2018.1430136. Epub 2018 Jan 30. Expert Opin Drug Discov. 2018. PMID: 29382242 Free PMC article. Review.
Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation.
Kielczewski JL, Jarajapu YP, McFarland EL, Cai J, Afzal A, Li Calzi S, Chang KH, Lydic T, Shaw LC, Busik J, Hughes J, Cardounel AJ, Wilson K, Lyons TJ, Boulton ME, Mames RN, Chan-Ling T, Grant MB. Kielczewski JL, et al. Among authors: busik j. Circ Res. 2009 Oct 23;105(9):897-905. doi: 10.1161/CIRCRESAHA.109.199059. Epub 2009 Sep 17. Circ Res. 2009. PMID: 19762684 Free PMC article.
Diabetic retinopathy is associated with bone marrow neuropathy and a depressed peripheral clock.
Busik JV, Tikhonenko M, Bhatwadekar A, Opreanu M, Yakubova N, Caballero S, Player D, Nakagawa T, Afzal A, Kielczewski J, Sochacki A, Hasty S, Li Calzi S, Kim S, Duclas SK, Segal MS, Guberski DL, Esselman WJ, Boulton ME, Grant MB. Busik JV, et al. J Exp Med. 2009 Dec 21;206(13):2897-906. doi: 10.1084/jem.20090889. Epub 2009 Nov 23. J Exp Med. 2009. PMID: 19934019 Free PMC article.
Free insulin-like growth factor binding protein-3 (IGFBP-3) reduces retinal vascular permeability in association with a reduction of acid sphingomyelinase (ASMase).
Kielczewski JL, Li Calzi S, Shaw LC, Cai J, Qi X, Ruan Q, Wu L, Liu L, Hu P, Chan-Ling T, Mames RN, Firth S, Baxter RC, Turowski P, Busik JV, Boulton ME, Grant MB. Kielczewski JL, et al. Among authors: busik jv. Invest Ophthalmol Vis Sci. 2011 Oct 21;52(11):8278-86. doi: 10.1167/iovs.11-8167. Invest Ophthalmol Vis Sci. 2011. PMID: 21931131 Free PMC article.
79 results