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Structure of the insulin receptor ectodomain reveals a folded-over conformation.
McKern NM, Lawrence MC, Streltsov VA, Lou MZ, Adams TE, Lovrecz GO, Elleman TC, Richards KM, Bentley JD, Pilling PA, Hoyne PA, Cartledge KA, Pham TM, Lewis JL, Sankovich SE, Stoichevska V, Da Silva E, Robinson CP, Frenkel MJ, Sparrow LG, Fernley RT, Epa VC, Ward CW. McKern NM, et al. Among authors: adams te. Nature. 2006 Sep 14;443(7108):218-21. doi: 10.1038/nature05106. Epub 2006 Sep 6. Nature. 2006. PMID: 16957736
Crystallization and preliminary X-ray analysis of the complexes between a Fab and two forms of human insulin-like growth factor II.
Newman J, Cohen EH, Cosgrove L, Kopacz K, Dransfield DT, Adams TE, Peat TS. Newman J, et al. Among authors: adams te. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Sep 1;65(Pt 9):945-8. doi: 10.1107/S1744309109024932. Epub 2009 Aug 26. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009. PMID: 19724140 Free PMC article.
Solution structure of ectodomains of the insulin receptor family: the ectodomain of the type 1 insulin-like growth factor receptor displays asymmetry of ligand binding accompanied by limited conformational change.
Whitten AE, Smith BJ, Menting JG, Margetts MB, McKern NM, Lovrecz GO, Adams TE, Richards K, Bentley JD, Trewhella J, Ward CW, Lawrence MC. Whitten AE, et al. Among authors: adams te. J Mol Biol. 2009 Dec 18;394(5):878-92. doi: 10.1016/j.jmb.2009.10.011. Epub 2009 Oct 14. J Mol Biol. 2009. PMID: 19835884
A human monoclonal antibody against insulin-like growth factor-II blocks the growth of human hepatocellular carcinoma cell lines in vitro and in vivo.
Dransfield DT, Cohen EH, Chang Q, Sparrow LG, Bentley JD, Dolezal O, Xiao X, Peat TS, Newman J, Pilling PA, Phan T, Priebe I, Brierley GV, Kastrapeli N, Kopacz K, Martik D, Wassaf D, Rank D, Conley G, Huang Y, Adams TE, Cosgrove L. Dransfield DT, et al. Among authors: adams te. Mol Cancer Ther. 2010 Jun;9(6):1809-19. doi: 10.1158/1535-7163.MCT-09-1134. Epub 2010 Jun 1. Mol Cancer Ther. 2010. PMID: 20515953
A new crystal form of human vascular adhesion protein 1.
Ernberg K, McGrath AP, Peat TS, Adams TE, Xiao X, Pham T, Newman J, McDonald IA, Collyer CA, Guss JM. Ernberg K, et al. Among authors: adams te. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Dec 1;66(Pt 12):1572-8. doi: 10.1107/S1744309110041515. Epub 2010 Nov 16. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 21139198 Free PMC article.
198 results