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IDH1 and IDH2 hotspot mutations are not found in canine glioma.
Reitman ZJ, Olby NJ, Mariani CL, Thomas R, Breen M, Bigner DD, McLendon RE, Yan H. Reitman ZJ, et al. Int J Cancer. 2010 Jul 1;127(1):245-6. doi: 10.1002/ijc.25017. Int J Cancer. 2010. PMID: 19877121 Free PMC article. No abstract available.
IDH1 and IDH2: not your typical oncogenes.
Reitman ZJ, Parsons DW, Yan H. Reitman ZJ, et al. Cancer Cell. 2010 Mar 16;17(3):215-6. doi: 10.1016/j.ccr.2010.02.024. Cancer Cell. 2010. PMID: 20227034 Free PMC article.
Enzyme redesign guided by cancer-derived IDH1 mutations.
Reitman ZJ, Choi BD, Spasojevic I, Bigner DD, Sampson JH, Yan H. Reitman ZJ, et al. Nat Chem Biol. 2012 Nov;8(11):887-9. doi: 10.1038/nchembio.1065. Epub 2012 Sep 23. Nat Chem Biol. 2012. PMID: 23001033 Free PMC article.
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.
Killela PJ, Reitman ZJ, Jiao Y, Bettegowda C, Agrawal N, Diaz LA Jr, Friedman AH, Friedman H, Gallia GL, Giovanella BC, Grollman AP, He TC, He Y, Hruban RH, Jallo GI, Mandahl N, Meeker AK, Mertens F, Netto GJ, Rasheed BA, Riggins GJ, Rosenquist TA, Schiffman M, Shih IeM, Theodorescu D, Torbenson MS, Velculescu VE, Wang TL, Wentzensen N, Wood LD, Zhang M, McLendon RE, Bigner DD, Kinzler KW, Vogelstein B, Papadopoulos N, Yan H. Killela PJ, et al. Among authors: reitman zj. Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6021-6. doi: 10.1073/pnas.1303607110. Epub 2013 Mar 25. Proc Natl Acad Sci U S A. 2013. PMID: 23530248 Free PMC article.
58 results