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Design and Syntheses of Highly Potent Teixobactin Analogues against Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus (MRSA), and Vancomycin-Resistant Enterococci (VRE) in Vitro and in Vivo.
J Med Chem. 2018 Mar 8;61(5):2009-2017. doi: 10.1021/acs.jmedchem.7b01634. Epub 2018 Feb 15.
J Med Chem. 2018.
PMID: 29363971
Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II binding.
Parmar A, Iyer A, Prior SH, Lloyd DG, Leng Goh ET, Vincent CS, Palmai-Pallag T, Bachrati CZ, Breukink E, Madder A, Lakshminarayanan R, Taylor EJ, Singh I.
Parmar A, et al. Among authors: leng goh et.
Chem Sci. 2017 Dec 1;8(12):8183-8192. doi: 10.1039/c7sc03241b. Epub 2017 Oct 5.
Chem Sci. 2017.
PMID: 29568465
Free PMC article.
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Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA).
Malkawi R, Iyer A, Parmar A, Lloyd DG, Leng Goh ET, Taylor EJ, Sarmad S, Madder A, Lakshminarayanan R, Singh I.
Malkawi R, et al. Among authors: leng goh et.
Pharmaceutics. 2018 Oct 11;10(4):183. doi: 10.3390/pharmaceutics10040183.
Pharmaceutics. 2018.
PMID: 30314324
Free PMC article.
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