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Design and Syntheses of Highly Potent Teixobactin Analogues against Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus (MRSA), and Vancomycin-Resistant Enterococci (VRE) in Vitro and in Vivo.
Parmar A, Lakshminarayanan R, Iyer A, Mayandi V, Leng Goh ET, Lloyd DG, Chalasani MLS, Verma NK, Prior SH, Beuerman RW, Madder A, Taylor EJ, Singh I. Parmar A, et al. Among authors: beuerman rw. J Med Chem. 2018 Mar 8;61(5):2009-2017. doi: 10.1021/acs.jmedchem.7b01634. Epub 2018 Feb 15. J Med Chem. 2018. PMID: 29363971
Protective Action of Linear Polyethylenimine against Staphylococcus aureus Colonization and Exaggerated Inflammation in Vitro and in Vivo.
Mayandi V, Sridhar S, Fazil MHUT, Goh ETL, Htoon HM, Orive G, Choong YK, Saravanan R, Beuerman RW, Barkham TMS, Yang L, Baskaran M, Jhanji V, Loh XJ, Verma NK, Lakshminarayanan R. Mayandi V, et al. Among authors: beuerman rw. ACS Infect Dis. 2019 Aug 9;5(8):1411-1422. doi: 10.1021/acsinfecdis.9b00102. Epub 2019 Jun 5. ACS Infect Dis. 2019. PMID: 31099239
Rational Substitution of ε-Lysine for α-Lysine Enhances the Cell and Membrane Selectivity of Pore-Forming Melittin.
Mayandi V, Xi Q, Leng ET, Koh SK, Jie TY, Barathi VA, Urf Turabe Fazil MH, Somaraju Chalasani ML, Varadarajan J, Ting DSJ, Beuerman RW, Chan LW, Agrawal R, Sebastian TM, Zhou L, Verma NK, Lakshminarayanan R. Mayandi V, et al. Among authors: beuerman rw. J Med Chem. 2020 Apr 9;63(7):3522-3537. doi: 10.1021/acs.jmedchem.9b01846. Epub 2020 Mar 30. J Med Chem. 2020. PMID: 32175733
Amino acid modified xanthone derivatives: novel, highly promising membrane-active antimicrobials for multidrug-resistant Gram-positive bacterial infections.
Koh JJ, Lin S, Aung TT, Lim F, Zou H, Bai Y, Li J, Lin H, Pang LM, Koh WL, Salleh SM, Lakshminarayanan R, Zhou L, Qiu S, Pervushin K, Verma C, Tan DT, Cao D, Liu S, Beuerman RW. Koh JJ, et al. Among authors: beuerman rw. J Med Chem. 2015 Jan 22;58(2):739-52. doi: 10.1021/jm501285x. Epub 2014 Dec 17. J Med Chem. 2015. PMID: 25474410
Antimicrobial Activity and Cell Selectivity of Synthetic and Biosynthetic Cationic Polymers.
Venkatesh M, Barathi VA, Goh ETL, Anggara R, Fazil MHUT, Ng AJY, Harini S, Aung TT, Fox SJ, Liu S, Yang L, Barkham TMS, Loh XJ, Verma NK, Beuerman RW, Lakshminarayanan R. Venkatesh M, et al. Among authors: beuerman rw. Antimicrob Agents Chemother. 2017 Sep 22;61(10):e00469-17. doi: 10.1128/AAC.00469-17. Print 2017 Oct. Antimicrob Agents Chemother. 2017. PMID: 28784676 Free PMC article.
327 results