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Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy.
Marrone L, Poser I, Casci I, Japtok J, Reinhardt P, Janosch A, Andree C, Lee HO, Moebius C, Koerner E, Reinhardt L, Cicardi ME, Hackmann K, Klink B, Poletti A, Alberti S, Bickle M, Hermann A, Pandey UB, Hyman AA, Sterneckert JL. Marrone L, et al. Among authors: sterneckert jl. Stem Cell Reports. 2018 Feb 13;10(2):375-389. doi: 10.1016/j.stemcr.2017.12.018. Epub 2018 Jan 18. Stem Cell Reports. 2018. PMID: 29358088 Free PMC article.
Zfp296 is a novel, pluripotent-specific reprogramming factor.
Fischedick G, Klein DC, Wu G, Esch D, Höing S, Han DW, Reinhardt P, Hergarten K, Tapia N, Schöler HR, Sterneckert JL. Fischedick G, et al. Among authors: sterneckert jl. PLoS One. 2012;7(4):e34645. doi: 10.1371/journal.pone.0034645. Epub 2012 Apr 2. PLoS One. 2012. PMID: 22485183 Free PMC article.
Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression.
Reinhardt P, Schmid B, Burbulla LF, Schöndorf DC, Wagner L, Glatza M, Höing S, Hargus G, Heck SA, Dhingra A, Wu G, Müller S, Brockmann K, Kluba T, Maisel M, Krüger R, Berg D, Tsytsyura Y, Thiel CS, Psathaki OE, Klingauf J, Kuhlmann T, Klewin M, Müller H, Gasser T, Schöler HR, Sterneckert J. Reinhardt P, et al. Cell Stem Cell. 2013 Mar 7;12(3):354-67. doi: 10.1016/j.stem.2013.01.008. Cell Stem Cell. 2013. PMID: 23472874 Free article.
Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling.
Reinhardt P, Glatza M, Hemmer K, Tsytsyura Y, Thiel CS, Höing S, Moritz S, Parga JA, Wagner L, Bruder JM, Wu G, Schmid B, Röpke A, Klingauf J, Schwamborn JC, Gasser T, Schöler HR, Sterneckert J. Reinhardt P, et al. PLoS One. 2013;8(3):e59252. doi: 10.1371/journal.pone.0059252. Epub 2013 Mar 22. PLoS One. 2013. PMID: 23533608 Free PMC article.
Investigating human disease using stem cell models.
Sterneckert JL, Reinhardt P, Schöler HR. Sterneckert JL, et al. Nat Rev Genet. 2014 Sep;15(9):625-39. doi: 10.1038/nrg3764. Epub 2014 Jul 29. Nat Rev Genet. 2014. PMID: 25069490 Review.
iPS cell derived neuronal cells for drug discovery.
Heilker R, Traub S, Reinhardt P, Schöler HR, Sterneckert J. Heilker R, et al. Trends Pharmacol Sci. 2014 Oct;35(10):510-9. doi: 10.1016/j.tips.2014.07.003. Epub 2014 Aug 3. Trends Pharmacol Sci. 2014. PMID: 25096281 Review.
Origin-dependent neural cell identities in differentiated human iPSCs in vitro and after transplantation into the mouse brain.
Hargus G, Ehrlich M, Araúzo-Bravo MJ, Hemmer K, Hallmann AL, Reinhardt P, Kim KP, Adachi K, Santourlidis S, Ghanjati F, Fauser M, Ossig C, Storch A, Kim JB, Schwamborn JC, Sterneckert J, Schöler HR, Kuhlmann T, Zaehres H. Hargus G, et al. Cell Rep. 2014 Sep 25;8(6):1697-1703. doi: 10.1016/j.celrep.2014.08.014. Epub 2014 Sep 15. Cell Rep. 2014. PMID: 25220454 Free article.
64 results