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Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy.
Marrone L, Poser I, Casci I, Japtok J, Reinhardt P, Janosch A, Andree C, Lee HO, Moebius C, Koerner E, Reinhardt L, Cicardi ME, Hackmann K, Klink B, Poletti A, Alberti S, Bickle M, Hermann A, Pandey UB, Hyman AA, Sterneckert JL. Marrone L, et al. Among authors: poletti a. Stem Cell Reports. 2018 Feb 13;10(2):375-389. doi: 10.1016/j.stemcr.2017.12.018. Epub 2018 Jan 18. Stem Cell Reports. 2018. PMID: 29358088 Free PMC article.
ALS-related misfolded protein management in motor neurons and muscle cells.
Galbiati M, Crippa V, Rusmini P, Cristofani R, Cicardi ME, Giorgetti E, Onesto E, Messi E, Poletti A. Galbiati M, et al. Among authors: poletti a. Neurochem Int. 2014 Dec;79:70-8. doi: 10.1016/j.neuint.2014.10.007. Epub 2014 Nov 6. Neurochem Int. 2014. PMID: 25451799 Review.
Transcriptional induction of the heat shock protein B8 mediates the clearance of misfolded proteins responsible for motor neuron diseases.
Crippa V, D'Agostino VG, Cristofani R, Rusmini P, Cicardi ME, Messi E, Loffredo R, Pancher M, Piccolella M, Galbiati M, Meroni M, Cereda C, Carra S, Provenzani A, Poletti A. Crippa V, et al. Among authors: poletti a. Sci Rep. 2016 Mar 10;6:22827. doi: 10.1038/srep22827. Sci Rep. 2016. PMID: 26961006 Free PMC article.
The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity.
Crippa V, Cicardi ME, Ramesh N, Seguin SJ, Ganassi M, Bigi I, Diacci C, Zelotti E, Baratashvili M, Gregory JM, Dobson CM, Cereda C, Pandey UB, Poletti A, Carra S. Crippa V, et al. Among authors: poletti a. Hum Mol Genet. 2016 Sep 15;25(18):3908-3924. doi: 10.1093/hmg/ddw232. Epub 2016 Jul 27. Hum Mol Genet. 2016. PMID: 27466192 Free PMC article.
The small heat shock protein B8 (HSPB8) efficiently removes aggregating species of dipeptides produced in C9ORF72-related neurodegenerative diseases.
Cristofani R, Crippa V, Vezzoli G, Rusmini P, Galbiati M, Cicardi ME, Meroni M, Ferrari V, Tedesco B, Piccolella M, Messi E, Carra S, Poletti A. Cristofani R, et al. Among authors: poletti a. Cell Stress Chaperones. 2018 Jan;23(1):1-12. doi: 10.1007/s12192-017-0806-9. Epub 2017 Jun 12. Cell Stress Chaperones. 2018. PMID: 28608264 Free PMC article.
Dual role of autophagy on docetaxel-sensitivity in prostate cancer cells.
Cristofani R, Montagnani Marelli M, Cicardi ME, Fontana F, Marzagalli M, Limonta P, Poletti A, Moretti RM. Cristofani R, et al. Among authors: poletti a. Cell Death Dis. 2018 Aug 30;9(9):889. doi: 10.1038/s41419-018-0866-5. Cell Death Dis. 2018. PMID: 30166521 Free PMC article.
301 results