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How do type II topoisomerases use ATP hydrolysis to simplify DNA topology beyond equilibrium? Investigating the relaxation reaction of nonsupercoiling type II topoisomerases.
Stuchinskaya T, Mitchenall LA, Schoeffler AJ, Corbett KD, Berger JM, Bates AD, Maxwell A. Stuchinskaya T, et al. Among authors: mitchenall la. J Mol Biol. 2009 Feb 6;385(5):1397-408. doi: 10.1016/j.jmb.2008.11.056. Epub 2008 Dec 7. J Mol Biol. 2009. PMID: 19094994 Free PMC article.
Single-molecule imaging of DNA gyrase activity in living Escherichia coli.
Stracy M, Wollman AJM, Kaja E, Gapinski J, Lee JE, Leek VA, McKie SJ, Mitchenall LA, Maxwell A, Sherratt DJ, Leake MC, Zawadzki P. Stracy M, et al. Among authors: mitchenall la. Nucleic Acids Res. 2019 Jan 10;47(1):210-220. doi: 10.1093/nar/gky1143. Nucleic Acids Res. 2019. PMID: 30445553 Free PMC article.
Structural and mechanistic analysis of ATPase inhibitors targeting mycobacterial DNA gyrase.
Henderson SR, Stevenson CEM, Malone B, Zholnerovych Y, Mitchenall LA, Pichowicz M, McGarry DH, Cooper IR, Charrier C, Salisbury AM, Lawson DM, Maxwell A. Henderson SR, et al. Among authors: mitchenall la. J Antimicrob Chemother. 2020 Oct 1;75(10):2835-2842. doi: 10.1093/jac/dkaa286. J Antimicrob Chemother. 2020. PMID: 32728686 Free PMC article.
Crystallization and preliminary X-ray analysis of a complex formed between the antibiotic simocyclinone D8 and the DNA breakage-reunion domain of Escherichia coli DNA gyrase.
Edwards MJ, Flatman RH, Mitchenall LA, Stevenson CE, Maxwell A, Lawson DM. Edwards MJ, et al. Among authors: mitchenall la. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Aug 1;65(Pt 8):846-8. doi: 10.1107/S1744309109028097. Epub 2009 Jul 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009. PMID: 19652356 Free PMC article.
40 results