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SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemia.
Johansson P, Klein-Hitpass L, Choidas A, Habenberger P, Mahboubi B, Kim B, Bergmann A, Scholtysik R, Brauser M, Lollies A, Siebert R, Zenz T, Dührsen U, Küppers R, Dürig J. Johansson P, et al. Among authors: kim b. Blood Cancer J. 2018 Jan 19;8(1):11. doi: 10.1038/s41408-017-0036-5. Blood Cancer J. 2018. PMID: 29352181 Free PMC article. Clinical Trial.
SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells.
Baldauf HM, Pan X, Erikson E, Schmidt S, Daddacha W, Burggraf M, Schenkova K, Ambiel I, Wabnitz G, Gramberg T, Panitz S, Flory E, Landau NR, Sertel S, Rutsch F, Lasitschka F, Kim B, König R, Fackler OT, Keppler OT. Baldauf HM, et al. Among authors: kim b. Nat Med. 2012 Nov;18(11):1682-7. doi: 10.1038/nm.2964. Nat Med. 2012. PMID: 22972397 Free PMC article.
SAMHD1 prevents autoimmunity by maintaining genome stability.
Kretschmer S, Wolf C, König N, Staroske W, Guck J, Häusler M, Luksch H, Nguyen LA, Kim B, Alexopoulou D, Dahl A, Rapp A, Cardoso MC, Shevchenko A, Lee-Kirsch MA. Kretschmer S, et al. Among authors: kim b. Ann Rheum Dis. 2015 Mar;74(3):e17. doi: 10.1136/annrheumdis-2013-204845. Epub 2014 Jan 20. Ann Rheum Dis. 2015. PMID: 24445253 Free PMC article.
Restrictive influence of SAMHD1 on Hepatitis B Virus life cycle.
Sommer AF, Rivière L, Qu B, Schott K, Riess M, Ni Y, Shepard C, Schnellbächer E, Finkernagel M, Himmelsbach K, Welzel K, Kettern N, Donnerhak C, Münk C, Flory E, Liese J, Kim B, Urban S, König R. Sommer AF, et al. Among authors: kim b. Sci Rep. 2016 May 27;6:26616. doi: 10.1038/srep26616. Sci Rep. 2016. PMID: 27229711 Free PMC article.
Substrates and Inhibitors of SAMHD1.
Hollenbaugh JA, Shelton J, Tao S, Amiralaei S, Liu P, Lu X, Goetze RW, Zhou L, Nettles JH, Schinazi RF, Kim B. Hollenbaugh JA, et al. Among authors: kim b. PLoS One. 2017 Jan 3;12(1):e0169052. doi: 10.1371/journal.pone.0169052. eCollection 2017. PLoS One. 2017. PMID: 28046007 Free PMC article.
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