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A novel anti-CD146 antibody specifically targets cancer cells by internalizing the molecule.
Nollet M, Stalin J, Moyon A, Traboulsi W, Essaadi A, Robert S, Malissen N, Bachelier R, Daniel L, Foucault-Bertaud A, Gaudy-Marqueste C, Lacroix R, Leroyer AS, Guillet B, Bardin N, Dignat-George F, Blot-Chabaud M. Nollet M, et al. Oncotarget. 2017 Nov 28;8(68):112283-112296. doi: 10.18632/oncotarget.22736. eCollection 2017 Dec 22. Oncotarget. 2017. PMID: 29348825 Free PMC article.
Soluble CD146 boosts therapeutic effect of endothelial progenitors through proteolytic processing of short CD146 isoform.
Stalin J, Harhouri K, Hubert L, Garrigue P, Nollet M, Essaadi A, Muller A, Foucault-Bertaud A, Bachelier R, Sabatier F, Pisano P, Peiretti F, Leroyer AS, Guillet B, Bardin N, Dignat-George F, Blot-Chabaud M. Stalin J, et al. Among authors: nollet m. Cardiovasc Res. 2016 Aug 1;111(3):240-51. doi: 10.1093/cvr/cvw096. Epub 2016 May 11. Cardiovasc Res. 2016. PMID: 27170199
Identification of CD146 as a novel molecular actor involved in systemic sclerosis.
Kaspi E, Heim X, Granel B, Guillet B, Stalin J, Nollet M, Bertaud-Foucault A, Robaglia-Schlupp A, Roll P, Cau P, Leroyer A, Bachelier R, Benyamine A, Dignat-George F, Blot-Chabaud M, Bardin N. Kaspi E, et al. Among authors: nollet m. J Allergy Clin Immunol. 2017 Nov;140(5):1448-1451.e6. doi: 10.1016/j.jaci.2017.04.046. Epub 2017 Jun 9. J Allergy Clin Immunol. 2017. PMID: 28606586 No abstract available.
Stem cell properties of peripheral blood endothelial progenitors are stimulated by soluble CD146 via miR-21: potential use in autologous cell therapy.
Essaadi A, Nollet M, Moyon A, Stalin J, Simoncini S, Balasse L, Bertaud A, Bachelier R, Leroyer AS, Sarlon G, Guillet B, Dignat-George F, Bardin N, Blot-Chabaud M. Essaadi A, et al. Among authors: nollet m. Sci Rep. 2018 Jun 20;8(1):9387. doi: 10.1038/s41598-018-27715-4. Sci Rep. 2018. PMID: 29925894 Free PMC article.
Therapeutic targeting of soluble CD146/MCAM with the M2J-1 monoclonal antibody prevents metastasis development and procoagulant activity in CD146-positive invasive tumors.
Stalin J, Traboulsi W, Vivancos-Stalin L, Nollet M, Joshkon A, Bachelier R, Guillet B, Lacroix R, Foucault-Bertaud A, Leroyer AS, Dignat-George F, Bardin N, Blot-Chabaud M. Stalin J, et al. Among authors: nollet m. Int J Cancer. 2020 Sep 15;147(6):1666-1679. doi: 10.1002/ijc.32909. Epub 2020 Feb 22. Int J Cancer. 2020. PMID: 32022257 Free article.
Involvement of Multiple Variants of Soluble CD146 in Systemic Sclerosis: Identification of a Novel Profibrotic Factor.
Nollet M, Bachelier R, Joshkon A, Traboulsi W, Mahieux A, Moyon A, Muller A, Somasundaram I, Simoncini S, Peiretti F, Leroyer AS, Guillet B, Granel B, Dignat-George F, Bardin N, Foucault-Bertaud A, Blot-Chabaud M. Nollet M, et al. Arthritis Rheumatol. 2022 Jun;74(6):1027-1038. doi: 10.1002/art.42063. Epub 2022 Apr 11. Arthritis Rheumatol. 2022. PMID: 35001552
CD146 at the Interface between Oxidative Stress and the Wnt Signaling Pathway in Systemic Sclerosis.
Heim X, Bermudez J, Joshkon A, Kaspi E, Bachelier R, Nollet M, Vélier M, Dou L, Brodovitch A, Foucault-Bertaud A, Leroyer AS, Benyamine A, Daumas A, Granel B, Sabatier F, Dignat-George F, Blot-Chabaud M, Bardin N. Heim X, et al. Among authors: nollet m. J Invest Dermatol. 2022 Dec;142(12):3200-3210.e5. doi: 10.1016/j.jid.2022.03.038. Epub 2022 Jun 9. J Invest Dermatol. 2022. PMID: 35690141 Free article.
Targeting soluble CD146 with a neutralizing antibody inhibits vascularization, growth and survival of CD146-positive tumors.
Stalin J, Nollet M, Garigue P, Fernandez S, Vivancos L, Essaadi A, Muller A, Bachelier R, Foucault-Bertaud A, Fugazza L, Leroyer AS, Bardin N, Guillet B, Dignat-George F, Blot-Chabaud M. Stalin J, et al. Among authors: nollet m. Oncogene. 2016 Oct 20;35(42):5489-5500. doi: 10.1038/onc.2016.83. Epub 2016 Apr 11. Oncogene. 2016. PMID: 27065325
35 results