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A novel anti-CD146 antibody specifically targets cancer cells by internalizing the molecule.
Oncotarget. 2017 Nov 28;8(68):112283-112296. doi: 10.18632/oncotarget.22736. eCollection 2017 Dec 22.
Oncotarget. 2017.
PMID: 29348825
Free PMC article.
Soluble CD146 boosts therapeutic effect of endothelial progenitors through proteolytic processing of short CD146 isoform.
Stalin J, Harhouri K, Hubert L, Garrigue P, Nollet M, Essaadi A, Muller A, Foucault-Bertaud A, Bachelier R, Sabatier F, Pisano P, Peiretti F, Leroyer AS, Guillet B, Bardin N, Dignat-George F, Blot-Chabaud M.
Stalin J, et al. Among authors: essaadi a.
Cardiovasc Res. 2016 Aug 1;111(3):240-51. doi: 10.1093/cvr/cvw096. Epub 2016 May 11.
Cardiovasc Res. 2016.
PMID: 27170199
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Stem cell properties of peripheral blood endothelial progenitors are stimulated by soluble CD146 via miR-21: potential use in autologous cell therapy.
Essaadi A, Nollet M, Moyon A, Stalin J, Simoncini S, Balasse L, Bertaud A, Bachelier R, Leroyer AS, Sarlon G, Guillet B, Dignat-George F, Bardin N, Blot-Chabaud M.
Essaadi A, et al.
Sci Rep. 2018 Jun 20;8(1):9387. doi: 10.1038/s41598-018-27715-4.
Sci Rep. 2018.
PMID: 29925894
Free PMC article.
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Targeting soluble CD146 with a neutralizing antibody inhibits vascularization, growth and survival of CD146-positive tumors.
Stalin J, Nollet M, Garigue P, Fernandez S, Vivancos L, Essaadi A, Muller A, Bachelier R, Foucault-Bertaud A, Fugazza L, Leroyer AS, Bardin N, Guillet B, Dignat-George F, Blot-Chabaud M.
Stalin J, et al. Among authors: essaadi a.
Oncogene. 2016 Oct 20;35(42):5489-5500. doi: 10.1038/onc.2016.83. Epub 2016 Apr 11.
Oncogene. 2016.
PMID: 27065325
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