Rodriguez JA - Search Results

1

Sub-ångström cryo-EM structure of a prion protofibril reveals a polar clasp.

Gallagher-Jones M, Glynn C, Boyer DR, Martynowycz MW, Hernandez E, Miao J, Zee CT, Novikova IV, Goldschmidt L, McFarlane HT, Helguera GF, Evans JE, Sawaya MR, Cascio D, Eisenberg DS, Gonen T, Rodriguez JA. Gallagher-Jones M, et al. Among authors: rodriguez ja. Nat Struct Mol Biol. 2018 Feb;25(2):131-134. doi: 10.1038/s41594-017-0018-0. Epub 2018 Jan 15. Nat Struct Mol Biol. 2018. PMID: 29335561 Free PMC article.

2

Cytokines fused to antibodies and their combinations as therapeutic agents against different peritoneal HER2/neu expressing tumors.

Helguera G, Rodríguez JA, Penichet ML. Helguera G, et al. Among authors: rodriguez ja. Mol Cancer Ther. 2006 Apr;5(4):1029-40. doi: 10.1158/1535-7163.MCT-05-0488. Mol Cancer Ther. 2006. PMID: 16648575

3

The transferrin receptor part I: Biology and targeting with cytotoxic antibodies for the treatment of cancer.

Daniels TR, Delgado T, Rodriguez JA, Helguera G, Penichet ML. Daniels TR, et al. Among authors: rodriguez ja. Clin Immunol. 2006 Nov;121(2):144-58. doi: 10.1016/j.clim.2006.06.010. Epub 2006 Aug 10. Clin Immunol. 2006. PMID: 16904380 Review.

4

Long-term immunity elicited by antibody-cytokine fusion proteins protects against sequential challenge with murine mammary and colon malignancies.

Helguera G, Rodríguez JA, Daniels TR, Penichet ML. Helguera G, et al. Among authors: rodriguez ja. Cancer Immunol Immunother. 2007 Sep;56(9):1507-12. doi: 10.1007/s00262-007-0297-0. Epub 2007 Feb 20. Cancer Immunol Immunother. 2007. PMID: 17310381 Free PMC article.

5

Binding specificity and internalization properties of an antibody-avidin fusion protein targeting the human transferrin receptor.

Rodríguez JA, Helguera G, Daniels TR, Neacato II, López-Valdés HE, Charles AC, Penichet ML. Rodríguez JA, et al. J Control Release. 2007 Dec 4;124(1-2):35-42. doi: 10.1016/j.jconrel.2007.08.020. Epub 2007 Aug 25. J Control Release. 2007. PMID: 17884229

6

Propulsion of African trypanosomes is driven by bihelical waves with alternating chirality separated by kinks.

Rodríguez JA, Lopez MA, Thayer MC, Zhao Y, Oberholzer M, Chang DD, Kisalu NK, Penichet ML, Helguera G, Bruinsma R, Hill KL, Miao J. Rodríguez JA, et al. Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19322-7. doi: 10.1073/pnas.0907001106. Epub 2009 Oct 30. Proc Natl Acad Sci U S A. 2009. PMID: 19880745 Free PMC article.

7

The transferrin receptor and the targeted delivery of therapeutic agents against cancer.

Daniels TR, Bernabeu E, Rodríguez JA, Patel S, Kozman M, Chiappetta DA, Holler E, Ljubimova JY, Helguera G, Penichet ML. Daniels TR, et al. Among authors: rodriguez ja. Biochim Biophys Acta. 2012 Mar;1820(3):291-317. doi: 10.1016/j.bbagen.2011.07.016. Epub 2011 Aug 5. Biochim Biophys Acta. 2012. PMID: 21851850 Free PMC article. Review.

8

Targeting HER2/neu with a fully human IgE to harness the allergic reaction against cancer cells.

Daniels TR, Leuchter RK, Quintero R, Helguera G, Rodríguez JA, Martínez-Maza O, Schultes BC, Nicodemus CF, Penichet ML. Daniels TR, et al. Among authors: rodriguez ja. Cancer Immunol Immunother. 2012 Jul;61(7):991-1003. doi: 10.1007/s00262-011-1150-z. Epub 2011 Nov 30. Cancer Immunol Immunother. 2012. PMID: 22127364 Free PMC article.

9

Insights into the mechanism of cell death induced by saporin delivered into cancer cells by an antibody fusion protein targeting the transferrin receptor 1.

Daniels-Wells TR, Helguera G, Rodríguez JA, Leoh LS, Erb MA, Diamante G, Casero D, Pellegrini M, Martínez-Maza O, Penichet ML. Daniels-Wells TR, et al. Among authors: rodriguez ja. Toxicol In Vitro. 2013 Feb;27(1):220-31. doi: 10.1016/j.tiv.2012.10.006. Epub 2012 Oct 17. Toxicol In Vitro. 2013. PMID: 23085102 Free PMC article.

10

Adaptive downregulation of mitochondrial function in down syndrome.

Helguera P, Seiglie J, Rodriguez J, Hanna M, Helguera G, Busciglio J. Helguera P, et al. Cell Metab. 2013 Jan 8;17(1):132-40. doi: 10.1016/j.cmet.2012.12.005. Cell Metab. 2013. PMID: 23312288 Free PMC article.

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