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Identification of a small-molecule compound that inhibits homodimerization of oncogenic NAC1 protein and sensitizes cancer cells to anticancer agents.
Wang X, Ji C, Zhang H, Shan Y, Ren Y, Hu Y, Shi L, Guo L, Zhu W, Xia Y, Liu B, Rong Z, Wu B, Ming Z, Ren X, Song J, Yang J, Zhang Y. Wang X, et al. Among authors: ren y, ren x. J Biol Chem. 2019 Jun 21;294(25):10006-10017. doi: 10.1074/jbc.RA119.007664. Epub 2019 May 17. J Biol Chem. 2019. PMID: 31101655 Free PMC article.
Autophagy in T-cell differentiation, survival and memory.
Wang L, Das JK, Kumar A, Peng HY, Ren Y, Xiong X, Yang JM, Song J. Wang L, et al. Among authors: ren y. Immunol Cell Biol. 2021 Apr;99(4):351-360. doi: 10.1111/imcb.12422. Epub 2020 Nov 24. Immunol Cell Biol. 2021. PMID: 33141986 Review.
NAC1 modulates autoimmunity by suppressing regulatory T cell-mediated tolerance.
Yang JM, Ren Y, Kumar A, Xiong X, Das JK, Peng HY, Wang L, Ren X, Zhang Y, Ji C, Cheng Y, Zhang L, Alaniz RC, de Figueiredo P, Fang D, Zhou H, Liu X, Wang J, Song J. Yang JM, et al. Among authors: ren y, ren x. Sci Adv. 2022 Jul;8(26):eabo0183. doi: 10.1126/sciadv.abo0183. Epub 2022 Jun 29. Sci Adv. 2022. PMID: 35767626 Free PMC article.
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