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Ligandomics: a paradigm shift in biological drug discovery.
Drug Discov Today. 2018 Mar;23(3):636-643. doi: 10.1016/j.drudis.2018.01.013. Epub 2018 Jan 8.
Drug Discov Today. 2018.
PMID: 29326083
Free PMC article.
Review.
Secretogranin III promotes angiogenesis through MEK/ERK signaling pathway.
Tang F, Pacheco MTF, Chen P, Liang D, Li W.
Tang F, et al. Among authors: pacheco mtf.
Biochem Biophys Res Commun. 2018 Jan 1;495(1):781-786. doi: 10.1016/j.bbrc.2017.11.080. Epub 2017 Nov 14.
Biochem Biophys Res Commun. 2018.
PMID: 29154827
Free PMC article.
Item in Clipboard
Amblyomin-X induces ER stress, mitochondrial dysfunction, and caspase activation in human melanoma and pancreatic tumor cell.
Morais KL, Pacheco MT, Berra CM, Bosch RV, Sciani JM, Chammas R, de Freitas Saito R, Iqbal A, Chudzinski-Tavassi AM.
Morais KL, et al.
Mol Cell Biochem. 2016 Apr;415(1-2):119-31. doi: 10.1007/s11010-016-2683-4. Epub 2016 Mar 25.
Mol Cell Biochem. 2016.
PMID: 27015684
Free PMC article.
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Tick salivary gland as potential natural source for the discovery of promising antitumor drug candidates.
Chudzinski-Tavassi AM, Morais KL, Pacheco MT, Pasqualoto KF, de Souza JG.
Chudzinski-Tavassi AM, et al.
Biomed Pharmacother. 2016 Feb;77:14-9. doi: 10.1016/j.biopha.2015.11.003. Epub 2015 Dec 3.
Biomed Pharmacother. 2016.
PMID: 26796259
Review.
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Specific role of cytoplasmic dynein in the mechanism of action of an antitumor molecule, Amblyomin-X.
Pacheco MT, Morais KL, Berra CM, Demasi M, Sciani JM, Branco VG, Bosch RV, Iqbal A, Chudzinski-Tavassi AM.
Pacheco MT, et al.
Exp Cell Res. 2016 Jan 15;340(2):248-58. doi: 10.1016/j.yexcr.2015.12.016. Epub 2015 Dec 31.
Exp Cell Res. 2016.
PMID: 26748183
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Dynein function and protein clearance changes in tumor cells induced by a Kunitz-type molecule, Amblyomin-X.
Pacheco MT, Berra CM, Morais KL, Sciani JM, Branco VG, Bosch RV, Chudzinski-Tavassi AM.
Pacheco MT, et al.
PLoS One. 2014 Dec 5;9(12):e111907. doi: 10.1371/journal.pone.0111907. eCollection 2014.
PLoS One. 2014.
PMID: 25479096
Free PMC article.
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Lopap: a non-inflammatory and cytoprotective molecule in neutrophils and endothelial cells.
Waismam K, Chudzinski-Tavassi AM, Carrijo-Carvalho LC, Pacheco MT, Farsky SH.
Waismam K, et al.
Toxicon. 2009 May;53(6):652-9. doi: 10.1016/j.toxicon.2009.01.031.
Toxicon. 2009.
PMID: 19673080
Free article.
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