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Anti-liver cancer activity in vitro and in vivo induced by 2-pyridyl 2,3-thiazole derivatives.
Dos Santos Silva TD, Bomfim LM, da Cruz Rodrigues ACB, Dias RB, Sales CBS, Rocha CAG, Soares MBP, Bezerra DP, de Oliveira Cardoso MV, Leite ACL, Militão GCG. Dos Santos Silva TD, et al. Among authors: bezerra dp. Toxicol Appl Pharmacol. 2017 Aug 15;329:212-223. doi: 10.1016/j.taap.2017.06.003. Epub 2017 Jun 10. Toxicol Appl Pharmacol. 2017. PMID: 28610992 Free article.
Novel piplartine-containing ruthenium complexes: synthesis, cell growth inhibition, apoptosis induction and ROS production on HCT116 cells.
D'Sousa Costa CO, Araujo Neto JH, Baliza IRS, Dias RB, Valverde LF, Vidal MTA, Sales CBS, Rocha CAG, Moreira DRM, Soares MBP, Batista AA, Bezerra DP. D'Sousa Costa CO, et al. Among authors: bezerra dp. Oncotarget. 2017 Nov 1;8(61):104367-104392. doi: 10.18632/oncotarget.22248. eCollection 2017 Nov 28. Oncotarget. 2017. PMID: 29262647 Free PMC article.
A novel ruthenium complex with xanthoxylin induces S-phase arrest and causes ERK1/2-mediated apoptosis in HepG2 cells through a p53-independent pathway.
de Carvalho NC, Neves SP, Dias RB, Valverde LF, Sales CBS, Rocha CAG, Soares MBP, Dos Santos ER, Oliveira RMM, Carlos RM, Nogueira PCL, Bezerra DP. de Carvalho NC, et al. Among authors: bezerra dp. Cell Death Dis. 2018 Jan 23;9(2):79. doi: 10.1038/s41419-017-0104-6. Cell Death Dis. 2018. PMID: 29362398 Free PMC article.
β-Lapachone and its iodine derivatives cause cell cycle arrest at G2/M phase and reactive oxygen species-mediated apoptosis in human oral squamous cell carcinoma cells.
Dias RB, de Araújo TBS, de Freitas RD, Rodrigues ACBDC, Sousa LP, Sales CBS, Valverde LF, Soares MBP, Dos Reis MG, Coletta RD, Ramos EAG, Camara CA, Silva TMS, Filho JMB, Bezerra DP, Rocha CAG. Dias RB, et al. Among authors: bezerra dp. Free Radic Biol Med. 2018 Oct;126:87-100. doi: 10.1016/j.freeradbiomed.2018.07.022. Epub 2018 Jul 30. Free Radic Biol Med. 2018. PMID: 30071298
A novel platinum complex containing a piplartine derivative exhibits enhanced cytotoxicity, causes oxidative stress and triggers apoptotic cell death by ERK/p38 pathway in human acute promyelocytic leukemia HL-60 cells.
Oliveira MS, Barbosa MIF, de Souza TB, Moreira DRM, Martins FT, Villarreal W, Machado RP, Doriguetto AC, Soares MBP, Bezerra DP. Oliveira MS, et al. Among authors: bezerra dp. Redox Biol. 2019 Jan;20:182-194. doi: 10.1016/j.redox.2018.10.006. Epub 2018 Oct 12. Redox Biol. 2019. PMID: 30359932 Free PMC article.
127 results