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Page 1
Genetic variants in COL13A1, ADIPOQ and SAMM50, in addition to the PNPLA3 gene, confer susceptibility to elevated transaminase levels in an admixed Mexican population.
Larrieta-Carrasco E, Flores YN, Macías-Kauffer LR, Ramírez-Palacios P, Quiterio M, Ramírez-Salazar EG, León-Mimila P, Rivera-Paredez B, Cabrera-Álvarez G, Canizales-Quinteros S, Zhang ZF, López-Pérez TV, Salmerón J, Velázquez-Cruz R. Larrieta-Carrasco E, et al. Exp Mol Pathol. 2018 Feb;104(1):50-58. doi: 10.1016/j.yexmp.2018.01.001. Epub 2018 Jan 4. Exp Mol Pathol. 2018. PMID: 29307798 Free PMC article.
The FTO gene is associated with adulthood obesity in the Mexican population.
Villalobos-Comparán M, Teresa Flores-Dorantes M, Teresa Villarreal-Molina M, Rodríguez-Cruz M, García-Ulloa AC, Robles L, Huertas-Vázquez A, Saucedo-Villarreal N, López-Alarcón M, Sánchez-Muñoz F, Domínguez-López A, Gutiérrez-Aguilar R, Menjivar M, Coral-Vázquez R, Hernández-Stengele G, Vital-Reyes VS, Acuña-Alonzo V, Romero-Hidalgo S, Ruiz-Gómez DG, Riaño-Barros D, Herrera MF, Gómez-Pérez FJ, Froguel P, García-García E, Teresa Tusié-Luna M, Aguilar-Salinas CA, Canizales-Quinteros S. Villalobos-Comparán M, et al. Obesity (Silver Spring). 2008 Oct;16(10):2296-301. doi: 10.1038/oby.2008.367. Epub 2008 Jul 31. Obesity (Silver Spring). 2008. PMID: 18719664 Free article.
A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans.
Acuña-Alonzo V, Flores-Dorantes T, Kruit JK, Villarreal-Molina T, Arellano-Campos O, Hünemeier T, Moreno-Estrada A, Ortiz-López MG, Villamil-Ramírez H, León-Mimila P, Villalobos-Comparan M, Jacobo-Albavera L, Ramírez-Jiménez S, Sikora M, Zhang LH, Pape TD, Granados-Silvestre Mde A, Montufar-Robles I, Tito-Alvarez AM, Zurita-Salinas C, Bustos-Arriaga J, Cedillo-Barrón L, Gómez-Trejo C, Barquera-Lozano R, Vieira-Filho JP, Granados J, Romero-Hidalgo S, Huertas-Vázquez A, González-Martín A, Gorostiza A, Bonatto SL, Rodríguez-Cruz M, Wang L, Tusié-Luna T, Aguilar-Salinas CA, Lisker R, Moises RS, Menjivar M, Salzano FM, Knowler WC, Bortolini MC, Hayden MR, Baier LJ, Canizales-Quinteros S. Acuña-Alonzo V, et al. Hum Mol Genet. 2010 Jul 15;19(14):2877-85. doi: 10.1093/hmg/ddq173. Epub 2010 Apr 23. Hum Mol Genet. 2010. PMID: 20418488 Free PMC article.
LOC387761 polymorphism is associated with type 2 diabetes in the Mexican population.
Gutiérrez-Vidal R, Rodríguez-Trejo A, Canizales-Quinteros S, Herrera-Cornejo M, Granados-Silvestre MA, Montúfar-Robles I, Ortiz-López MG, Menjívar M. Gutiérrez-Vidal R, et al. Genet Test Mol Biomarkers. 2011 Jan-Feb;15(1-2):79-83. doi: 10.1089/gtmb.2010.0107. Epub 2011 Jan 3. Genet Test Mol Biomarkers. 2011. PMID: 21198374
PCSK1 rs6232 is associated with childhood and adult class III obesity in the Mexican population.
Villalobos-Comparán M, Villamil-Ramírez H, Villarreal-Molina T, Larrieta-Carrasco E, León-Mimila P, Romero-Hidalgo S, Jacobo-Albavera L, Liceaga-Fuentes AE, Campos-Pérez FJ, López-Contreras BE, Tusié-Luna T, Del Río-Navarro BE, Aguilar-Salinas CA, Canizales-Quinteros S. Villalobos-Comparán M, et al. PLoS One. 2012;7(6):e39037. doi: 10.1371/journal.pone.0039037. Epub 2012 Jun 21. PLoS One. 2012. PMID: 22737226 Free PMC article.
VNN1 gene expression levels and the G-137T polymorphism are associated with HDL-C levels in Mexican prepubertal children.
Jacobo-Albavera L, Aguayo-de la Rosa PI, Villarreal-Molina T, Villamil-Ramírez H, León-Mimila P, Romero-Hidalgo S, López-Contreras BE, Sánchez-Muñoz F, Bojalil R, González-Barrios JA, Aguilar-Salinas CA, Canizales-Quinteros S. Jacobo-Albavera L, et al. PLoS One. 2012;7(11):e49818. doi: 10.1371/journal.pone.0049818. Epub 2012 Nov 21. PLoS One. 2012. PMID: 23185446 Free PMC article.
Association of the I148M/PNPLA3 variant with elevated alanine transaminase levels in normal-weight and overweight/obese Mexican children.
Larrieta-Carrasco E, León-Mimila P, Villarreal-Molina T, Villamil-Ramírez H, Romero-Hidalgo S, Jacobo-Albavera L, Gutiérrez-Vidal R, López-Contreras BE, Guillén-Pineda LE, Sánchez-Muñoz F, Bojalil R, Mejía-Domínguez AM, Méndez-Sánchez N, Domínguez-López A, Aguilar-Salinas CA, Canizales-Quinteros S. Larrieta-Carrasco E, et al. Gene. 2013 May 15;520(2):185-8. doi: 10.1016/j.gene.2013.03.038. Epub 2013 Mar 17. Gene. 2013. PMID: 23510779
Contribution of common genetic variants to obesity and obesity-related traits in mexican children and adults.
León-Mimila P, Villamil-Ramírez H, Villalobos-Comparán M, Villarreal-Molina T, Romero-Hidalgo S, López-Contreras B, Gutiérrez-Vidal R, Vega-Badillo J, Jacobo-Albavera L, Posadas-Romeros C, Canizalez-Román A, Río-Navarro BD, Campos-Pérez F, Acuña-Alonzo V, Aguilar-Salinas C, Canizales-Quinteros S. León-Mimila P, et al. PLoS One. 2013 Aug 8;8(8):e70640. doi: 10.1371/journal.pone.0070640. eCollection 2013. PLoS One. 2013. PMID: 23950976 Free PMC article.
PNPLA3 I148M polymorphism is associated with elevated alanine transaminase levels in Mexican Indigenous and Mestizo populations.
Larrieta-Carrasco E, Acuña-Alonzo V, Velázquez-Cruz R, Barquera-Lozano R, León-Mimila P, Villamil-Ramírez H, Menjivar M, Romero-Hidalgo S, Méndez-Sánchez N, Cárdenas V, Bañuelos-Moreno M, Flores YN, Quiterio M, Salmerón J, Sánchez-Muñoz F, Villarreal-Molina T, Aguilar-Salinas CA, Canizales-Quinteros S. Larrieta-Carrasco E, et al. Mol Biol Rep. 2014 Jul;41(7):4705-11. doi: 10.1007/s11033-014-3341-0. Epub 2014 Apr 2. Mol Biol Rep. 2014. PMID: 24691744
Admixture in Latin America: geographic structure, phenotypic diversity and self-perception of ancestry based on 7,342 individuals.
Ruiz-Linares A, Adhikari K, Acuña-Alonzo V, Quinto-Sanchez M, Jaramillo C, Arias W, Fuentes M, Pizarro M, Everardo P, de Avila F, Gómez-Valdés J, León-Mimila P, Hunemeier T, Ramallo V, Silva de Cerqueira CC, Burley MW, Konca E, de Oliveira MZ, Veronez MR, Rubio-Codina M, Attanasio O, Gibbon S, Ray N, Gallo C, Poletti G, Rosique J, Schuler-Faccini L, Salzano FM, Bortolini MC, Canizales-Quinteros S, Rothhammer F, Bedoya G, Balding D, Gonzalez-José R. Ruiz-Linares A, et al. PLoS Genet. 2014 Sep 25;10(9):e1004572. doi: 10.1371/journal.pgen.1004572. eCollection 2014 Sep. PLoS Genet. 2014. PMID: 25254375 Free PMC article.
143 results