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Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor.
Che T, Majumdar S, Zaidi SA, Ondachi P, McCorvy JD, Wang S, Mosier PD, Uprety R, Vardy E, Krumm BE, Han GW, Lee MY, Pardon E, Steyaert J, Huang XP, Strachan RT, Tribo AR, Pasternak GW, Carroll FI, Stevens RC, Cherezov V, Katritch V, Wacker D, Roth BL. Che T, et al. Among authors: zaidi sa. Cell. 2018 Jan 11;172(1-2):55-67.e15. doi: 10.1016/j.cell.2017.12.011. Epub 2018 Jan 4. Cell. 2018. PMID: 29307491 Free PMC article.
Binding mode characterization of 6α- and 6β-N-heterocyclic substituted naltrexamine derivatives via docking in opioid receptor crystal structures and site-directed mutagenesis studies: application of the 'message-address' concept in development of mu opioid receptor selective antagonists.
Zaidi SA, Arnatt CK, He H, Selley DE, Mosier PD, Kellogg GE, Zhang Y. Zaidi SA, et al. Bioorg Med Chem. 2013 Nov 1;21(21):6405-13. doi: 10.1016/j.bmc.2013.08.042. Epub 2013 Sep 4. Bioorg Med Chem. 2013. PMID: 24055076 Free PMC article.
Design, syntheses, and pharmacological characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan analogues as opioid receptor ligands.
Yuan Y, Zaidi SA, Stevens DL, Scoggins KL, Mosier PD, Kellogg GE, Dewey WL, Selley DE, Zhang Y. Yuan Y, et al. Among authors: zaidi sa. Bioorg Med Chem. 2015 Apr 15;23(8):1701-15. doi: 10.1016/j.bmc.2015.02.055. Epub 2015 Mar 6. Bioorg Med Chem. 2015. PMID: 25783191 Free PMC article.
Crystal structure of the Frizzled 4 receptor in a ligand-free state.
Yang S, Wu Y, Xu TH, de Waal PW, He Y, Pu M, Chen Y, DeBruine ZJ, Zhang B, Zaidi SA, Popov P, Guo Y, Han GW, Lu Y, Suino-Powell K, Dong S, Harikumar KG, Miller LJ, Katritch V, Xu HE, Shui W, Stevens RC, Melcher K, Zhao S, Xu F. Yang S, et al. Among authors: zaidi sa. Nature. 2018 Aug;560(7720):666-670. doi: 10.1038/s41586-018-0447-x. Epub 2018 Aug 22. Nature. 2018. PMID: 30135577
Harnessing Ion-Binding Sites for GPCR Pharmacology.
Zarzycka B, Zaidi SA, Roth BL, Katritch V. Zarzycka B, et al. Among authors: zaidi sa. Pharmacol Rev. 2019 Oct;71(4):571-595. doi: 10.1124/pr.119.017863. Pharmacol Rev. 2019. PMID: 31551350 Free PMC article. Review.
193 results