Taylor DL - Search Results

1

Clinically Observed Estrogen Receptor Alpha Mutations within the Ligand-Binding Domain Confer Distinguishable Phenotypes.

Jia S, Miedel MT, Ngo M, Hessenius R, Chen N, Wang P, Bahreini A, Li Z, Ding Z, Shun TY, Zuckerman DM, Taylor DL, Puhalla SL, Lee AV, Oesterreich S, Stern AM. Jia S, et al. Among authors: taylor dl. Oncology. 2018;94(3):176-189. doi: 10.1159/000485510. Epub 2018 Jan 6. Oncology. 2018. PMID: 29306943 Free PMC article.

2

Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery.

Gough AH, Chen N, Shun TY, Lezon TR, Boltz RC, Reese CE, Wagner J, Vernetti LA, Grandis JR, Lee AV, Stern AM, Schurdak ME, Taylor DL. Gough AH, et al. Among authors: taylor dl. PLoS One. 2014 Jul 18;9(7):e102678. doi: 10.1371/journal.pone.0102678. eCollection 2014. PLoS One. 2014. PMID: 25036749 Free PMC article.

3

Proteomic Screening and Lasso Regression Reveal Differential Signaling in Insulin and Insulin-like Growth Factor I (IGF1) Pathways.

Erdem C, Nagle AM, Casa AJ, Litzenburger BC, Wang YF, Taylor DL, Lee AV, Lezon TR. Erdem C, et al. Among authors: taylor dl. Mol Cell Proteomics. 2016 Sep;15(9):3045-57. doi: 10.1074/mcp.M115.057729. Epub 2016 Jun 30. Mol Cell Proteomics. 2016. PMID: 27364358 Free PMC article.

4

The Microphysiology Systems Database for Analyzing and Modeling Compound Interactions with Human and Animal Organ Models.

Gough A, Vernetti L, Bergenthal L, Shun TY, Taylor DL. Gough A, et al. Among authors: taylor dl. Appl In Vitro Toxicol. 2016 Jun 1;2(2):103-117. doi: 10.1089/aivt.2016.0011. Appl In Vitro Toxicol. 2016. PMID: 28781990 Free PMC article.

5

Integrating Analysis of Cellular Heterogeneity in High-Content Dose-Response Studies.

Gough A, Shun TY, Taylor DL, Schurdak M. Gough A, et al. Among authors: taylor dl. Methods Mol Biol. 2018;1745:25-46. doi: 10.1007/978-1-4939-7680-5_2. Methods Mol Biol. 2018. PMID: 29476461

6

A Quantitative Systems Pharmacology Approach to Infer Pathways Involved in Complex Disease Phenotypes.

Schurdak ME, Pei F, Lezon TR, Carlisle D, Friedlander R, Taylor DL, Stern AM. Schurdak ME, et al. Among authors: taylor dl. Methods Mol Biol. 2018;1787:207-222. doi: 10.1007/978-1-4939-7847-2_16. Methods Mol Biol. 2018. PMID: 29736721

7

Modeling the Effect of the Metastatic Microenvironment on Phenotypes Conferred by Estrogen Receptor Mutations Using a Human Liver Microphysiological System.

Miedel MT, Gavlock DC, Jia S, Gough A, Taylor DL, Stern AM. Miedel MT, et al. Among authors: taylor dl. Sci Rep. 2019 Jun 6;9(1):8341. doi: 10.1038/s41598-019-44756-5. Sci Rep. 2019. PMID: 31171849 Free PMC article.

8

Targeting NAD⁺ Biosynthesis Overcomes Panobinostat and Bortezomib-Induced Malignant Glioma Resistance.

Jane EP, Premkumar DR, Thambireddy S, Golbourn B, Agnihotri S, Bertrand KC, Mack SC, Myers MI, Chattopadhyay A, Taylor DL, Schurdak ME, Stern AM, Pollack IF. Jane EP, et al. Among authors: taylor dl. Mol Cancer Res. 2020 Jul;18(7):1004-1017. doi: 10.1158/1541-7786.MCR-19-0669. Epub 2020 Apr 1. Mol Cancer Res. 2020. PMID: 32238439 Free PMC article.

9

Inhibition of RPS6K reveals context-dependent Akt activity in luminal breast cancer cells.

Erdem C, Lee AV, Taylor DL, Lezon TR. Erdem C, et al. Among authors: taylor dl. PLoS Comput Biol. 2021 Jun 30;17(6):e1009125. doi: 10.1371/journal.pcbi.1009125. eCollection 2021 Jun. PLoS Comput Biol. 2021. PMID: 34191793 Free PMC article.

10

A Quantitative Systems Pharmacology Platform Reveals NAFLD Pathophysiological States and Targeting Strategies.

Lefever DE, Miedel MT, Pei F, DiStefano JK, Debiasio R, Shun TY, Saydmohammed M, Chikina M, Vernetti LA, Soto-Gutierrez A, Monga SP, Bataller R, Behari J, Yechoor VK, Bahar I, Gough A, Stern AM, Taylor DL. Lefever DE, et al. Among authors: taylor dl. Metabolites. 2022 Jun 7;12(6):528. doi: 10.3390/metabo12060528. Metabolites. 2022. PMID: 35736460 Free PMC article.

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