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Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors.
Kalin JH, Wu M, Gomez AV, Song Y, Das J, Hayward D, Adejola N, Wu M, Panova I, Chung HJ, Kim E, Roberts HJ, Roberts JM, Prusevich P, Jeliazkov JR, Roy Burman SS, Fairall L, Milano C, Eroglu A, Proby CM, Dinkova-Kostova AT, Hancock WW, Gray JJ, Bradner JE, Valente S, Mai A, Anders NM, Rudek MA, Hu Y, Ryu B, Schwabe JWR, Mattevi A, Alani RM, Cole PA. Kalin JH, et al. Among authors: fairall l. Nat Commun. 2018 Jan 4;9(1):53. doi: 10.1038/s41467-017-02242-4. Nat Commun. 2018. PMID: 29302039 Free PMC article.
Towards an understanding of protein-DNA recognition.
Rhodes D, Schwabe JW, Chapman L, Fairall L. Rhodes D, et al. Among authors: fairall l. Philos Trans R Soc Lond B Biol Sci. 1996 Apr 29;351(1339):501-9. doi: 10.1098/rstb.1996.0048. Philos Trans R Soc Lond B Biol Sci. 1996. PMID: 8735272 Review.
Structural basis for the activation of PPARgamma by oxidized fatty acids.
Itoh T, Fairall L, Amin K, Inaba Y, Szanto A, Balint BL, Nagy L, Yamamoto K, Schwabe JW. Itoh T, et al. Among authors: fairall l. Nat Struct Mol Biol. 2008 Sep;15(9):924-31. doi: 10.1038/nsmb.1474. Nat Struct Mol Biol. 2008. PMID: 19172745 Free PMC article.
Negative regulation by nuclear receptors: a plethora of mechanisms.
Santos GM, Fairall L, Schwabe JW. Santos GM, et al. Among authors: fairall l. Trends Endocrinol Metab. 2011 Mar;22(3):87-93. doi: 10.1016/j.tem.2010.11.004. Epub 2010 Dec 31. Trends Endocrinol Metab. 2011. PMID: 21196123 Free PMC article. Review.
Nuclear hormone receptor co-repressors: structure and function.
Watson PJ, Fairall L, Schwabe JW. Watson PJ, et al. Among authors: fairall l. Mol Cell Endocrinol. 2012 Jan 30;348(2):440-9. doi: 10.1016/j.mce.2011.08.033. Epub 2011 Sep 8. Mol Cell Endocrinol. 2012. PMID: 21925568 Free PMC article. Review.
Class I HDACs share a common mechanism of regulation by inositol phosphates.
Millard CJ, Watson PJ, Celardo I, Gordiyenko Y, Cowley SM, Robinson CV, Fairall L, Schwabe JW. Millard CJ, et al. Among authors: fairall l. Mol Cell. 2013 Jul 11;51(1):57-67. doi: 10.1016/j.molcel.2013.05.020. Epub 2013 Jun 20. Mol Cell. 2013. PMID: 23791785 Free PMC article.
155 results