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Structural insights into humanization of anti-tissue factor antibody 10H10.
Teplyakov A, Obmolova G, Malia TJ, Raghunathan G, Martinez C, Fransson J, Edwards W, Connor J, Husovsky M, Beck H, Chi E, Fenton S, Zhou H, Almagro JC, Gilliland GL. Teplyakov A, et al. Among authors: gilliland gl. MAbs. 2018 Feb/Mar;10(2):269-277. doi: 10.1080/19420862.2017.1412026. Epub 2018 Jan 2. MAbs. 2018. PMID: 29283291 Free PMC article.
Human framework adaptation of a mouse anti-human IL-13 antibody.
Fransson J, Teplyakov A, Raghunathan G, Chi E, Cordier W, Dinh T, Feng Y, Giles-Komar J, Gilliland G, Lollo B, Malia TJ, Nishioka W, Obmolova G, Zhao S, Zhao Y, Swanson RV, Almagro JC. Fransson J, et al. J Mol Biol. 2010 Apr 30;398(2):214-31. doi: 10.1016/j.jmb.2010.03.004. Epub 2010 Mar 10. J Mol Biol. 2010. PMID: 20226193
Structural diversity in a human antibody germline library.
Teplyakov A, Obmolova G, Malia TJ, Luo J, Muzammil S, Sweet R, Almagro JC, Gilliland GL. Teplyakov A, et al. Among authors: gilliland gl. MAbs. 2016 Aug-Sep;8(6):1045-63. doi: 10.1080/19420862.2016.1190060. Epub 2016 May 21. MAbs. 2016. PMID: 27210805 Free PMC article.
Noncanonical conformation of CDR L1 in the anti-IL-23 antibody CNTO4088.
Teplyakov A, Obmolova G, Rogers A, Gilliland GL. Teplyakov A, et al. Among authors: gilliland gl. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Mar 1;66(Pt 3):229-32. doi: 10.1107/S1744309109054141. Epub 2010 Feb 23. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20208149 Free PMC article.
On the domain pairing in chimeric antibodies.
Teplyakov A, Obmolova G, Carton JM, Gao W, Zhao Y, Gilliland GL. Teplyakov A, et al. Among authors: gilliland gl. Mol Immunol. 2010 Aug;47(14):2422-6. doi: 10.1016/j.molimm.2010.05.002. Mol Immunol. 2010. PMID: 20554002
Coevolution of antibody stability and Vκ CDR-L3 canonical structure.
Luo J, Obmolova G, Huang A, Strake B, Teplyakov A, Malia T, Muzammil S, Zhao Y, Gilliland GL, Feng Y. Luo J, et al. Among authors: gilliland gl. J Mol Biol. 2010 Oct 1;402(4):708-19. doi: 10.1016/j.jmb.2010.08.009. Epub 2010 Aug 18. J Mol Biol. 2010. PMID: 20727359
177 results