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3,4-diaminopyridine base effectively treats the weakness of Lambert-Eaton myasthenia.
Muscle Nerve. 2018 Apr;57(4):561-568. doi: 10.1002/mus.26052. Epub 2018 Feb 2.
Muscle Nerve. 2018.
PMID: 29280483
Free PMC article.
Clinical Trial.
Population Pharmacokinetics/Pharmacodynamics of 3,4-Diaminopyridine Free Base in Patients With Lambert-Eaton Myasthenia.
Thakkar N, Guptill JT, Aleš K, Jacobus D, Jacobus L, Peloquin C, Cohen-Wolkowiez M, Gonzalez D; DAPPER Study Group.
Thakkar N, et al.
CPT Pharmacometrics Syst Pharmacol. 2017 Sep;6(9):625-634. doi: 10.1002/psp4.12218. Epub 2017 Jul 24.
CPT Pharmacometrics Syst Pharmacol. 2017.
PMID: 28623849
Free PMC article.
Clinical Trial.
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Validation of the triple timed up-and-go test in Lambert-Eaton myasthenia.
Raja SM, Sanders DB, Juel VC, Harati Y, Smith AG, Pascuzzi R, Richman DP, Wu A, Aleš KL, Jacobus LR, Jacobus DP, Guptill JT; DAPPER Study Team.
Raja SM, et al. Among authors: jacobus lr.
Muscle Nerve. 2019 Sep;60(3):292-298. doi: 10.1002/mus.26625. Epub 2019 Jul 18.
Muscle Nerve. 2019.
PMID: 31269226
Free PMC article.
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Lead Selection of a New Aminomethylphenol, JPC-3210, for Malaria Treatment and Prevention.
Chavchich M, Birrell GW, Ager AL, MacKenzie DO, Heffernan GD, Schiehser GA, Jacobus LR, Shanks GD, Jacobus DP, Edstein MD.
Chavchich M, et al. Among authors: jacobus lr.
Antimicrob Agents Chemother. 2016 Apr 22;60(5):3115-8. doi: 10.1128/AAC.03066-15. Print 2016 May.
Antimicrob Agents Chemother. 2016.
PMID: 26856849
Free PMC article.
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JPC-2997, a new aminomethylphenol with high in vitro and in vivo antimalarial activities against blood stages of Plasmodium.
Birrell GW, Chavchich M, Ager AL, Shieh HM, Heffernan GD, Zhao W, Krasucki PE, Saionz KW, Terpinski J, Schiehser GA, Jacobus LR, Shanks GD, Jacobus DP, Edstein MD.
Birrell GW, et al. Among authors: jacobus lr.
Antimicrob Agents Chemother. 2015 Jan;59(1):170-7. doi: 10.1128/AAC.03762-14. Epub 2014 Oct 20.
Antimicrob Agents Chemother. 2015.
PMID: 25331702
Free PMC article.
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Characterization of the Preclinical Pharmacology of the New 2-Aminomethylphenol, JPC-3210, for Malaria Treatment and Prevention.
Birrell GW, Heffernan GD, Schiehser GA, Anderson J, Ager AL, Morales P, MacKenzie D, van Breda K, Chavchich M, Jacobus LR, Shanks GD, Jacobus DP, Edstein MD.
Birrell GW, et al. Among authors: jacobus lr.
Antimicrob Agents Chemother. 2018 Mar 27;62(4):e01335-17. doi: 10.1128/AAC.01335-17. Print 2018 Apr.
Antimicrob Agents Chemother. 2018.
PMID: 29311093
Free PMC article.
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ABDOMINAL ALLERGY IN INFANCY.
Stafford HE, Watson RG, Jacobus LR.
Stafford HE, et al. Among authors: jacobus lr.
Cal West Med. 1931 Mar;34(3):168-72.
Cal West Med. 1931.
PMID: 18741685
Free PMC article.
No abstract available.
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