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The Hidden Genomic and Transcriptomic Plasticity of Giant Marker Chromosomes in Cancer.
Macchia G, Severgnini M, Purgato S, Tolomeo D, Casciaro H, Cifola I, L'Abbate A, Loverro A, Palumbo O, Carella M, Bianchini L, Perini G, De Bellis G, Mertens F, Rocchi M, Storlazzi CT. Macchia G, et al. Genetics. 2018 Mar;208(3):951-961. doi: 10.1534/genetics.117.300552. Epub 2017 Dec 26. Genetics. 2018. PMID: 29279323 Free PMC article.
Genomic organization and evolution of double minutes/homogeneously staining regions with MYC amplification in human cancer.
L'Abbate A, Macchia G, D'Addabbo P, Lonoce A, Tolomeo D, Trombetta D, Kok K, Bartenhagen C, Whelan CW, Palumbo O, Severgnini M, Cifola I, Dugas M, Carella M, De Bellis G, Rocchi M, Carbone L, Storlazzi CT. L'Abbate A, et al. Among authors: macchia g. Nucleic Acids Res. 2014 Aug;42(14):9131-45. doi: 10.1093/nar/gku590. Epub 2014 Jul 17. Nucleic Acids Res. 2014. PMID: 25034695 Free PMC article.
Ring chromosomes, breakpoint clusters, and neocentromeres in sarcomas.
Macchia G, Nord KH, Zoli M, Purgato S, D'Addabbo P, Whelan CW, Carbone L, Perini G, Mertens F, Rocchi M, Storlazzi CT. Macchia G, et al. Genes Chromosomes Cancer. 2015 Mar;54(3):156-67. doi: 10.1002/gcc.22228. Epub 2014 Nov 25. Genes Chromosomes Cancer. 2015. PMID: 25421174
Concurrent chromothripsis events in a case of TP53 depleted acute myeloid leukemia with myelodysplasia-related changes.
Tolomeo D, L'Abbate A, Lonoce A, D'Addabbo P, Miccoli MF, Lo Cunsolo C, Iuzzolino P, Palumbo O, Carella M, Racanelli V, Mazza T, Ottaviani E, Martinelli G, Macchia G, Storlazzi CT. Tolomeo D, et al. Among authors: macchia g. Cancer Genet. 2019 Sep;237:63-68. doi: 10.1016/j.cancergen.2019.06.009. Epub 2019 Jun 12. Cancer Genet. 2019. PMID: 31447067
Gene amplification as double minutes or homogeneously staining regions in solid tumors: origin and structure.
Storlazzi CT, Lonoce A, Guastadisegni MC, Trombetta D, D'Addabbo P, Daniele G, L'Abbate A, Macchia G, Surace C, Kok K, Ullmann R, Purgato S, Palumbo O, Carella M, Ambros PF, Rocchi M. Storlazzi CT, et al. Among authors: macchia g. Genome Res. 2010 Sep;20(9):1198-206. doi: 10.1101/gr.106252.110. Epub 2010 Jul 14. Genome Res. 2010. PMID: 20631050 Free PMC article.
396 results