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Effects of Y361-auto-phosphorylation on structural plasticity of the HIPK2 kinase domain.
Scaglione A, Monteonofrio L, Parisi G, Cecchetti C, Siepi F, Rinaldo C, Giorgi A, Verzili D, Zamparelli C, Savino C, Soddu S, Vallone B, Montemiglio LC. Scaglione A, et al. Among authors: parisi g. Protein Sci. 2018 Mar;27(3):725-737. doi: 10.1002/pro.3367. Epub 2017 Dec 28. Protein Sci. 2018. PMID: 29277937 Free PMC article.
Substrate-induced conformational change in cytochrome P450 OleP.
Parisi G, Montemiglio LC, Giuffrè A, Macone A, Scaglione A, Cerutti G, Exertier C, Savino C, Vallone B. Parisi G, et al. FASEB J. 2019 Feb;33(2):1787-1800. doi: 10.1096/fj.201800450RR. Epub 2018 Sep 12. FASEB J. 2019. PMID: 30207799
Data reported herein provide structural snapshots of key precatalytic steps in the OleP reaction and explain how structural rearrangements induced by substrate binding regulate activity.-Parisi, G., Montemiglio, L. C., Giuffre, A., Macone, A., Scaglione, A., Cerutti …
Data reported herein provide structural snapshots of key precatalytic steps in the OleP reaction and explain how structural rearrangements i …
Neuroglobin, clues to function and mechanism.
Exertier C, Montemiglio LC, Freda I, Gugole E, Parisi G, Savino C, Vallone B. Exertier C, et al. Among authors: parisi g. Mol Aspects Med. 2022 Apr;84:101055. doi: 10.1016/j.mam.2021.101055. Epub 2021 Dec 6. Mol Aspects Med. 2022. PMID: 34876274 Review.
Point Mutations at a Key Site Alter the Cytochrome P450 OleP Structural Dynamics.
Montemiglio LC, Gugole E, Freda I, Exertier C, D'Auria L, Chen CG, Nardi AN, Cerutti G, Parisi G, D'Abramo M, Savino C, Vallone B. Montemiglio LC, et al. Among authors: parisi g. Biomolecules. 2021 Dec 31;12(1):55. doi: 10.3390/biom12010055. Biomolecules. 2021. PMID: 35053203 Free PMC article.
Probing the Role of Murine Neuroglobin CDloop-D-Helix Unit in CO Ligand Binding and Structural Dynamics.
Exertier C, Sebastiani F, Freda I, Gugole E, Cerutti G, Parisi G, Montemiglio LC, Becucci M, Viappiani C, Bruno S, Savino C, Zamparelli C, Anselmi M, Abbruzzetti S, Smulevich G, Vallone B. Exertier C, et al. Among authors: parisi g. ACS Chem Biol. 2022 Aug 19;17(8):2099-2108. doi: 10.1021/acschembio.2c00172. Epub 2022 Jul 7. ACS Chem Biol. 2022. PMID: 35797699 Free PMC article.
719 results