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MK2-TNF-Signaling Comes Full Circle.
Menon MB, Gaestel M. Menon MB, et al. Among authors: gaestel m. Trends Biochem Sci. 2018 Mar;43(3):170-179. doi: 10.1016/j.tibs.2017.12.002. Epub 2017 Dec 21. Trends Biochem Sci. 2018. PMID: 29275999 Review.
Distinct cellular functions of MK2.
Kotlyarov A, Yannoni Y, Fritz S, Laass K, Telliez JB, Pitman D, Lin LL, Gaestel M. Kotlyarov A, et al. Among authors: gaestel m. Mol Cell Biol. 2002 Jul;22(13):4827-35. doi: 10.1128/MCB.22.13.4827-4835.2002. Mol Cell Biol. 2002. PMID: 12052889 Free PMC article.
Gene deletion of MK2 inhibits TNF-alpha and IL-6 and protects against cerulein-induced pancreatitis.
Tietz AB, Malo A, Diebold J, Kotlyarov A, Herbst A, Kolligs FT, Brandt-Nedelev B, Halangk W, Gaestel M, Göke B, Schäfer C. Tietz AB, et al. Among authors: gaestel m. Am J Physiol Gastrointest Liver Physiol. 2006 Jun;290(6):G1298-306. doi: 10.1152/ajpgi.00530.2005. Epub 2006 Jan 19. Am J Physiol Gastrointest Liver Physiol. 2006. PMID: 16423921 Free article.
Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element.
Hitti E, Iakovleva T, Brook M, Deppenmeier S, Gruber AD, Radzioch D, Clark AR, Blackshear PJ, Kotlyarov A, Gaestel M. Hitti E, et al. Among authors: gaestel m. Mol Cell Biol. 2006 Mar;26(6):2399-407. doi: 10.1128/MCB.26.6.2399-2407.2006. Mol Cell Biol. 2006. PMID: 16508014 Free PMC article.
The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK.
Ronkina N, Kotlyarov A, Dittrich-Breiholz O, Kracht M, Hitti E, Milarski K, Askew R, Marusic S, Lin LL, Gaestel M, Telliez JB. Ronkina N, et al. Among authors: gaestel m. Mol Cell Biol. 2007 Jan;27(1):170-81. doi: 10.1128/MCB.01456-06. Epub 2006 Oct 9. Mol Cell Biol. 2007. PMID: 17030606 Free PMC article.
271 results