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mTORC1 Signaling: A Double-Edged Sword in Diabetic β Cells.
Ardestani A, Lupse B, Kido Y, Leibowitz G, Maedler K. Ardestani A, et al. Among authors: kido y. Cell Metab. 2018 Feb 6;27(2):314-331. doi: 10.1016/j.cmet.2017.11.004. Epub 2017 Dec 21. Cell Metab. 2018. PMID: 29275961 Free article. Review.
Ablation of TSC2 enhances insulin secretion by increasing the number of mitochondria through activation of mTORC1.
Koyanagi M, Asahara S, Matsuda T, Hashimoto N, Shigeyama Y, Shibutani Y, Kanno A, Fuchita M, Mikami T, Hosooka T, Inoue H, Matsumoto M, Koike M, Uchiyama Y, Noda T, Seino S, Kasuga M, Kido Y. Koyanagi M, et al. Among authors: kido y. PLoS One. 2011;6(8):e23238. doi: 10.1371/journal.pone.0023238. Epub 2011 Aug 19. PLoS One. 2011. PMID: 21886784 Free PMC article.
Histone deacetylase regulates insulin signaling via two pathways in pancreatic β cells.
Kawada Y, Asahara SI, Sugiura Y, Sato A, Furubayashi A, Kawamura M, Bartolome A, Terashi-Suzuki E, Takai T, Kanno A, Koyanagi-Kimura M, Matsuda T, Hashimoto N, Kido Y. Kawada Y, et al. Among authors: kido y. PLoS One. 2017 Sep 8;12(9):e0184435. doi: 10.1371/journal.pone.0184435. eCollection 2017. PLoS One. 2017. PMID: 28886131 Free PMC article.
Histone deacetylase 6 regulates insulin signaling in pancreatic β cells.
Inoue H, Asahara SI, Sugiura Y, Kawada Y, Imai A, Hara C, Kanno A, Kimura-Koyanagi M, Kido Y. Inoue H, et al. Among authors: kido y. Biochem Biophys Res Commun. 2021 Jan 1;534:896-901. doi: 10.1016/j.bbrc.2020.10.078. Epub 2020 Nov 6. Biochem Biophys Res Commun. 2021. PMID: 33168187
Pancreatic β-cell failure mediated by mTORC1 hyperactivity and autophagic impairment.
Bartolomé A, Kimura-Koyanagi M, Asahara S, Guillén C, Inoue H, Teruyama K, Shimizu S, Kanno A, García-Aguilar A, Koike M, Uchiyama Y, Benito M, Noda T, Kido Y. Bartolomé A, et al. Among authors: kido y. Diabetes. 2014 Sep;63(9):2996-3008. doi: 10.2337/db13-0970. Epub 2014 Apr 16. Diabetes. 2014. PMID: 24740570
GCN2 regulates pancreatic β cell mass by sensing intracellular amino acid levels.
Kanno A, Asahara SI, Furubayashi A, Masuda K, Yoshitomi R, Suzuki E, Takai T, Kimura-Koyanagi M, Matsuda T, Bartolome A, Hirota Y, Yokoi N, Inaba Y, Inoue H, Matsumoto M, Inoue K, Abe T, Wei FY, Tomizawa K, Ogawa W, Seino S, Kasuga M, Kido Y. Kanno A, et al. Among authors: kido y. JCI Insight. 2020 May 7;5(9):e128820. doi: 10.1172/jci.insight.128820. JCI Insight. 2020. PMID: 32376799 Free PMC article.
570 results