Lo WL - Search Results

1

TCR Signaling: Mechanisms of Initiation and Propagation.

Courtney AH, Lo WL, Weiss A. Courtney AH, et al. Among authors: lo wl. Trends Biochem Sci. 2018 Feb;43(2):108-123. doi: 10.1016/j.tibs.2017.11.008. Epub 2017 Dec 18. Trends Biochem Sci. 2018. PMID: 29269020 Free PMC article. Review.

2

Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT.

Lo WL, Shah NH, Ahsan N, Horkova V, Stepanek O, Salomon AR, Kuriyan J, Weiss A. Lo WL, et al. Nat Immunol. 2018 Jul;19(7):733-741. doi: 10.1038/s41590-018-0131-1. Epub 2018 Jun 18. Nat Immunol. 2018. PMID: 29915297 Free PMC article.

3

Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination.

Lo WL, Shah NH, Rubin SA, Zhang W, Horkova V, Fallahee IR, Stepanek O, Zon LI, Kuriyan J, Weiss A. Lo WL, et al. Nat Immunol. 2019 Nov;20(11):1481-1493. doi: 10.1038/s41590-019-0502-2. Epub 2019 Oct 14. Nat Immunol. 2019. PMID: 31611699 Free PMC article.

4

CD45 functions as a signaling gatekeeper in T cells.

Courtney AH, Shvets AA, Lu W, Griffante G, Mollenauer M, Horkova V, Lo WL, Yu S, Stepanek O, Chakraborty AK, Weiss A. Courtney AH, et al. Among authors: lo wl. Sci Signal. 2019 Oct 22;12(604):eaaw8151. doi: 10.1126/scisignal.aaw8151. Sci Signal. 2019. PMID: 31641081 Free PMC article.

5

How the T cell signaling network processes information to discriminate between self and agonist ligands.

Ganti RS, Lo WL, McAffee DB, Groves JT, Weiss A, Chakraborty AK. Ganti RS, et al. Among authors: lo wl. Proc Natl Acad Sci U S A. 2020 Oct 20;117(42):26020-26030. doi: 10.1073/pnas.2008303117. Epub 2020 Oct 5. Proc Natl Acad Sci U S A. 2020. PMID: 33020303 Free PMC article.

6

Itk Promotes the Integration of TCR and CD28 Costimulation through Its Direct Substrates SLP-76 and Gads.

Hallumi E, Shalah R, Lo WL, Corso J, Oz I, Beach D, Wittman S, Isenberg A, Sela M, Urlaub H, Weiss A, Yablonski D. Hallumi E, et al. Among authors: lo wl. J Immunol. 2021 May 15;206(10):2322-2337. doi: 10.4049/jimmunol.2001053. Epub 2021 Apr 30. J Immunol. 2021. PMID: 33931484 Free PMC article.

7

Adapting T Cell Receptor Ligand Discrimination Capability via LAT.

Lo WL, Weiss A. Lo WL, et al. Front Immunol. 2021 Apr 16;12:673196. doi: 10.3389/fimmu.2021.673196. eCollection 2021. Front Immunol. 2021. PMID: 33936119 Free PMC article. Review.

8

ZAP70, too little, too much can lead to autoimmunity.

Ashouri JF, Lo WL, Nguyen TTT, Shen L, Weiss A. Ashouri JF, et al. Among authors: lo wl. Immunol Rev. 2022 May;307(1):145-160. doi: 10.1111/imr.13058. Epub 2021 Dec 18. Immunol Rev. 2022. PMID: 34923645 Free PMC article. Review.

9

A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function.

Lo WL, Kuhlmann M, Rizzuto G, Ekiz HA, Kolawole EM, Revelo MP, Andargachew R, Li Z, Tsai YL, Marson A, Evavold BD, Zehn D, Weiss A. Lo WL, et al. Nat Immunol. 2023 Apr;24(4):676-689. doi: 10.1038/s41590-023-01444-x. Epub 2023 Mar 13. Nat Immunol. 2023. PMID: 36914891 Free PMC article.

10

Self-peptides in TCR repertoire selection and peripheral T cell function.

Lo WL, Allen PM. Lo WL, et al. Curr Top Microbiol Immunol. 2014;373:49-67. doi: 10.1007/82_2013_319. Curr Top Microbiol Immunol. 2014. PMID: 23612987 Review.

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