Ungefroren H - Search Results

1

The Role of PAR2 in TGF-β1-Induced ERK Activation and Cell Motility.

Ungefroren H, Witte D, Fiedler C, Gädeken T, Kaufmann R, Lehnert H, Gieseler F, Rauch BH. Ungefroren H, et al. Int J Mol Sci. 2017 Dec 20;18(12):2776. doi: 10.3390/ijms18122776. Int J Mol Sci. 2017. PMID: 29261154 Free PMC article.

2

Transforming growth factor-beta (TGF-beta) type I receptor/ALK5-dependent activation of the GADD45beta gene mediates the induction of biglycan expression by TGF-beta.

Ungefroren H, Groth S, Ruhnke M, Kalthoff H, Fändrich F. Ungefroren H, et al. J Biol Chem. 2005 Jan 28;280(4):2644-52. doi: 10.1074/jbc.M411925200. Epub 2004 Nov 16. J Biol Chem. 2005. PMID: 15546867 Free article.

We have recently shown that induction of biglycan (BGN) expression by transforming growth factor-beta1 (TGF-beta1) required sequential activation of both Smad and p38 mitogen-activated protein kinase signaling (Ungefroren, H., Lenschow, W., Chen, W.-B., and Kalthoff …

We have recently shown that induction of biglycan (BGN) expression by transforming growth factor-beta1 (TGF-beta1) required sequential activ …

3

Antitumor activity of ALK1 in pancreatic carcinoma cells.

Ungefroren H, Schniewind B, Groth S, Chen WB, Müerköster SS, Kalthoff H, Fändrich F. Ungefroren H, et al. Int J Cancer. 2007 Apr 15;120(8):1641-51. doi: 10.1002/ijc.22393. Int J Cancer. 2007. PMID: 17230504 Free article.

4

Differential roles of Src in transforming growth factor-ß regulation of growth arrest, epithelial-to-mesenchymal transition and cell migration in pancreatic ductal adenocarcinoma cells.

Ungefroren H, Sebens S, Groth S, Gieseler F, Fändrich F. Ungefroren H, et al. Int J Oncol. 2011 Mar;38(3):797-805. doi: 10.3892/ijo.2011.897. Epub 2011 Jan 11. Int J Oncol. 2011. PMID: 21225226

5

The Src family kinase inhibitors PP2 and PP1 block TGF-beta1-mediated cellular responses by direct and differential inhibition of type I and type II TGF-beta receptors.

Ungefroren H, Sebens S, Groth S, Gieseler F, Fändrich F. Ungefroren H, et al. Curr Cancer Drug Targets. 2011 May;11(4):524-35. doi: 10.2174/156800911795538075. Curr Cancer Drug Targets. 2011. PMID: 21395548

6

Differential roles of Smad2 and Smad3 in the regulation of TGF-β1-mediated growth inhibition and cell migration in pancreatic ductal adenocarcinoma cells: control by Rac1.

Ungefroren H, Groth S, Sebens S, Lehnert H, Gieseler F, Fändrich F. Ungefroren H, et al. Mol Cancer. 2011 May 30;10:67. doi: 10.1186/1476-4598-10-67. Mol Cancer. 2011. PMID: 21624123 Free PMC article.

7

Interaction of tumor cells with the microenvironment.

Ungefroren H, Sebens S, Seidl D, Lehnert H, Hass R. Ungefroren H, et al. Cell Commun Signal. 2011 Sep 13;9:18. doi: 10.1186/1478-811X-9-18. Cell Commun Signal. 2011. PMID: 21914164 Free PMC article.

8

The Src family kinase inhibitors PP2 and PP1 effectively block TGF-beta1-induced cell migration and invasion in both established and primary carcinoma cells.

Bartscht T, Lehnert H, Gieseler F, Ungefroren H. Bartscht T, et al. Among authors: ungefroren h. Cancer Chemother Pharmacol. 2012 Aug;70(2):221-30. doi: 10.1007/s00280-012-1904-0. Epub 2012 Jun 15. Cancer Chemother Pharmacol. 2012. PMID: 22699812

9

Characterization of spontaneous and TGF-β-induced cell motility of primary human normal and neoplastic mammary cells in vitro using novel real-time technology.

Mandel K, Seidl D, Rades D, Lehnert H, Gieseler F, Hass R, Ungefroren H. Mandel K, et al. Among authors: ungefroren h. PLoS One. 2013;8(2):e56591. doi: 10.1371/journal.pone.0056591. Epub 2013 Feb 14. PLoS One. 2013. PMID: 23457587 Free PMC article.

10

Proteinase-activated receptors (PARs) - focus on receptor-receptor-interactions and their physiological and pathophysiological impact.

Gieseler F, Ungefroren H, Settmacher U, Hollenberg MD, Kaufmann R. Gieseler F, et al. Among authors: ungefroren h. Cell Commun Signal. 2013 Nov 11;11:86. doi: 10.1186/1478-811X-11-86. Cell Commun Signal. 2013. PMID: 24215724 Free PMC article. Review.

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