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Cyclobutanone Mimics of Intermediates in Metallo-β-Lactamase Catalysis.
Abboud MI, Kosmopoulou M, Krismanich AP, Johnson JW, Hinchliffe P, Brem J, Claridge TDW, Spencer J, Schofield CJ, Dmitrienko GI. Abboud MI, et al. Among authors: kosmopoulou m. Chemistry. 2018 Apr 17;24(22):5734-5737. doi: 10.1002/chem.201705886. Epub 2018 Jan 17. Chemistry. 2018. PMID: 29250863 Free PMC article.
Cross-class metallo-β-lactamase inhibition by bisthiazolidines reveals multiple binding modes.
Hinchliffe P, González MM, Mojica MF, González JM, Castillo V, Saiz C, Kosmopoulou M, Tooke CL, Llarrull LI, Mahler G, Bonomo RA, Vila AJ, Spencer J. Hinchliffe P, et al. Among authors: kosmopoulou m. Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):E3745-54. doi: 10.1073/pnas.1601368113. Epub 2016 Jun 14. Proc Natl Acad Sci U S A. 2016. PMID: 27303030 Free PMC article.
Bisthiazolidines: A Substrate-Mimicking Scaffold as an Inhibitor of the NDM-1 Carbapenemase.
González MM, Kosmopoulou M, Mojica MF, Castillo V, Hinchliffe P, Pettinati I, Brem J, Schofield CJ, Mahler G, Bonomo RA, Llarrull LI, Spencer J, Vila AJ. González MM, et al. Among authors: kosmopoulou m. ACS Infect Dis. 2015 Nov 13;1(11):544-54. doi: 10.1021/acsinfecdis.5b00046. Epub 2015 Jul 20. ACS Infect Dis. 2015. PMID: 27623409 Free PMC article.
Exploring the Role of Residue 228 in Substrate and Inhibitor Recognition by VIM Metallo-β-lactamases.
Mojica MF, Mahler SG, Bethel CR, Taracila MA, Kosmopoulou M, Papp-Wallace KM, Llarrull LI, Wilson BM, Marshall SH, Wallace CJ, Villegas MV, Harris ME, Vila AJ, Spencer J, Bonomo RA. Mojica MF, et al. Among authors: kosmopoulou m. Biochemistry. 2015 May 26;54(20):3183-96. doi: 10.1021/acs.biochem.5b00106. Epub 2015 May 12. Biochemistry. 2015. PMID: 25915520 Free PMC article.
Binding of N-acetyl-N '-beta-D-glucopyranosyl urea and N-benzoyl-N '-beta-D-glucopyranosyl urea to glycogen phosphorylase b: kinetic and crystallographic studies.
Oikonomakos NG, Kosmopoulou M, Zographos SE, Leonidas DD, Chrysina ED, Somsák L, Nagy V, Praly JP, Docsa T, Tóth B, Gergely P. Oikonomakos NG, et al. Among authors: kosmopoulou m. Eur J Biochem. 2002 Mar;269(6):1684-96. doi: 10.1046/j.1432-1327.2002.02813.x. Eur J Biochem. 2002. PMID: 11895439 Free article.
29 results