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Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis.
Esther CR Jr, Muhlebach MS, Ehre C, Hill DB, Wolfgang MC, Kesimer M, Ramsey KA, Markovetz MR, Garbarine IC, Forest MG, Seim I, Zorn B, Morrison CB, Delion MF, Thelin WR, Villalon D, Sabater JR, Turkovic L, Ranganathan S, Stick SM, Boucher RC. Esther CR Jr, et al. Among authors: seim i. Sci Transl Med. 2019 Apr 3;11(486):eaav3488. doi: 10.1126/scitranslmed.aav3488. Sci Transl Med. 2019. PMID: 30944166 Free PMC article.
Mucus and mucus flake composition and abundance reflect inflammatory and infection status in cystic fibrosis.
Markovetz MR, Garbarine IC, Morrison CB, Kissner WJ, Seim I, Forest MG, Papanikolas MJ, Freeman R, Ceppe A, Ghio A, Alexis NE, Stick SM, Ehre C, Boucher RC, Esther CR, Muhlebach MS, Hill DB. Markovetz MR, et al. Among authors: seim i. J Cyst Fibros. 2022 Nov;21(6):959-966. doi: 10.1016/j.jcf.2022.04.008. Epub 2022 Apr 16. J Cyst Fibros. 2022. PMID: 35437233
Double-stranded RNA drives SARS-CoV-2 nucleocapsid protein to undergo phase separation at specific temperatures.
Roden CA, Dai Y, Giannetti CA, Seim I, Lee M, Sealfon R, McLaughlin GA, Boerneke MA, Iserman C, Wey SA, Ekena JL, Troyanskaya OG, Weeks KM, You L, Chilkoti A, Gladfelter AS. Roden CA, et al. Among authors: seim i. Nucleic Acids Res. 2022 Aug 12;50(14):8168-8192. doi: 10.1093/nar/gkac596. Nucleic Acids Res. 2022. PMID: 35871289 Free PMC article.
Membrane surfaces regulate assembly of ribonucleoprotein condensates.
Snead WT, Jalihal AP, Gerbich TM, Seim I, Hu Z, Gladfelter AS. Snead WT, et al. Among authors: seim i. Nat Cell Biol. 2022 Apr;24(4):461-470. doi: 10.1038/s41556-022-00882-3. Epub 2022 Apr 11. Nat Cell Biol. 2022. PMID: 35411085 Free PMC article.
Designed, highly expressing, thermostable dengue virus 2 envelope protein dimers elicit quaternary epitope antibodies.
Kudlacek ST, Metz S, Thiono D, Payne AM, Phan TTN, Tian S, Forsberg LJ, Maguire J, Seim I, Zhang S, Tripathy A, Harrison J, Nicely NI, Soman S, McCracken MK, Gromowski GD, Jarman RG, Premkumar L, de Silva AM, Kuhlman B. Kudlacek ST, et al. Among authors: seim i. Sci Adv. 2021 Oct 15;7(42):eabg4084. doi: 10.1126/sciadv.abg4084. Epub 2021 Oct 15. Sci Adv. 2021. PMID: 34652943 Free PMC article.
99 results