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MEK/ERK addiction in CNL/aCML.
Kesarwani M, Kincaid Z, Azam M. Kesarwani M, et al. Among authors: kincaid z. Oncotarget. 2017 Nov 3;8(59):99215-99216. doi: 10.18632/oncotarget.22283. eCollection 2017 Nov 21. Oncotarget. 2017. PMID: 29245892 Free PMC article. No abstract available.
Enhanced MAPK signaling is essential for CSF3R-induced leukemia.
Rohrabaugh S, Kesarwani M, Kincaid Z, Huber E, Leddonne J, Siddiqui Z, Khalifa Y, Komurov K, Grimes HL, Azam M. Rohrabaugh S, et al. Among authors: kincaid z. Leukemia. 2017 Aug;31(8):1770-1778. doi: 10.1038/leu.2016.376. Epub 2016 Dec 27. Leukemia. 2017. PMID: 28031554 Free PMC article.
Momelotinib is a highly potent inhibitor of FLT3-mutant AML.
Azhar M, Kincaid Z, Kesarwani M, Ahmed A, Wunderlich M, Latif T, Starczynowski D, Azam M. Azhar M, et al. Among authors: kincaid z. Blood Adv. 2022 Feb 22;6(4):1186-1192. doi: 10.1182/bloodadvances.2021004611. Blood Adv. 2022. PMID: 34768286 Free PMC article.
Rational polypharmacological targeting of FLT3, JAK2, ABL, and ERK1 suppresses the adaptive resistance to FLT3 inhibitors in AML.
Azhar M, Kincaid Z, Kesarwani M, Menke J, Schwieterman J, Ansari S, Reaves A, Ahmed A, Shehzad R, Khan A, Syed N, Amir N, Wunderlich M, Latif T, Seibel W, Azam M. Azhar M, et al. Among authors: kincaid z. Blood Adv. 2023 Apr 25;7(8):1460-1476. doi: 10.1182/bloodadvances.2022007486. Blood Adv. 2023. PMID: 36044389 Free PMC article.
MAPK-negative feedback regulation confers dependence to JAK2V617F signaling.
Kesarwani M, Kincaid Z, Azhar M, Menke J, Schwieterman J, Ansari S, Reaves A, Deininger ME, Levine R, Grimes HL, Azam M. Kesarwani M, et al. Among authors: kincaid z. Leukemia. 2023 Aug;37(8):1686-1697. doi: 10.1038/s41375-023-01959-0. Epub 2023 Jul 10. Leukemia. 2023. PMID: 37430058 Free PMC article.
12 results