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An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes.
Partridge FA, Brown AE, Buckingham SD, Willis NJ, Wynne GM, Forman R, Else KJ, Morrison AA, Matthews JB, Russell AJ, Lomas DA, Sattelle DB. Partridge FA, et al. Among authors: sattelle db. Int J Parasitol Drugs Drug Resist. 2018 Apr;8(1):8-21. doi: 10.1016/j.ijpddr.2017.11.004. Epub 2017 Dec 2. Int J Parasitol Drugs Drug Resist. 2018. PMID: 29223747 Free PMC article.
Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo.
Partridge FA, Murphy EA, Willis NJ, Bataille CJ, Forman R, Heyer-Chauhan N, Marinič B, Sowood DJ, Wynne GM, Else KJ, Russell AJ, Sattelle DB. Partridge FA, et al. Among authors: sattelle db. PLoS Negl Trop Dis. 2017 Feb 9;11(2):e0005359. doi: 10.1371/journal.pntd.0005359. eCollection 2017 Feb. PLoS Negl Trop Dis. 2017. PMID: 28182663 Free PMC article.
2,4-Diaminothieno[3,2-d]pyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm.
Partridge FA, Forman R, Willis NJ, Bataille CJR, Murphy EA, Brown AE, Heyer-Chauhan N, Marinič B, Sowood DJC, Wynne GM, Else KJ, Russell AJ, Sattelle DB. Partridge FA, et al. Among authors: sattelle db. PLoS Negl Trop Dis. 2018 Jul 11;12(7):e0006487. doi: 10.1371/journal.pntd.0006487. eCollection 2018 Jul. PLoS Negl Trop Dis. 2018. PMID: 29995893 Free PMC article.
Automated phenotyping of mosquito larvae enables high-throughput screening for novel larvicides and offers potential for smartphone-based detection of larval insecticide resistance.
Buckingham SD, Partridge FA, Poulton BC, Miller BS, McKendry RA, Lycett GJ, Sattelle DB. Buckingham SD, et al. Among authors: sattelle db. PLoS Negl Trop Dis. 2021 Jun 3;15(6):e0008639. doi: 10.1371/journal.pntd.0008639. eCollection 2021 Jun. PLoS Negl Trop Dis. 2021. PMID: 34081710 Free PMC article.
Chemistry-to-gene screens in Caenorhabditis elegans.
Jones AK, Buckingham SD, Sattelle DB. Jones AK, et al. Among authors: sattelle db. Nat Rev Drug Discov. 2005 Apr;4(4):321-30. doi: 10.1038/nrd1692. Nat Rev Drug Discov. 2005. PMID: 15803195 Review.
Strategies for automated analysis of C. elegans locomotion.
Buckingham SD, Sattelle DB. Buckingham SD, et al. Among authors: sattelle db. Invert Neurosci. 2008 Sep;8(3):121-31. doi: 10.1007/s10158-008-0077-3. Epub 2008 Aug 8. Invert Neurosci. 2008. PMID: 18688666 Review.
276 results