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An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes.
Partridge FA, Brown AE, Buckingham SD, Willis NJ, Wynne GM, Forman R, Else KJ, Morrison AA, Matthews JB, Russell AJ, Lomas DA, Sattelle DB. Partridge FA, et al. Int J Parasitol Drugs Drug Resist. 2018 Apr;8(1):8-21. doi: 10.1016/j.ijpddr.2017.11.004. Epub 2017 Dec 2. Int J Parasitol Drugs Drug Resist. 2018. PMID: 29223747 Free PMC article.
The fungal alkaloid Okaramine-B activates an L-glutamate-gated chloride channel from Ixodes scapularis, a tick vector of Lyme disease.
Furutani S, Ihara M, Lees K, Buckingham SD, Partridge FA, David JA, Patel R, Warchal S, Mellor IR, Matsuda K, Sattelle DB. Furutani S, et al. Among authors: partridge fa. Int J Parasitol Drugs Drug Resist. 2018 Aug;8(2):350-360. doi: 10.1016/j.ijpddr.2018.06.001. Epub 2018 Jun 4. Int J Parasitol Drugs Drug Resist. 2018. PMID: 29957333 Free PMC article.
2,4-Diaminothieno[3,2-d]pyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm.
Partridge FA, Forman R, Willis NJ, Bataille CJR, Murphy EA, Brown AE, Heyer-Chauhan N, Marinič B, Sowood DJC, Wynne GM, Else KJ, Russell AJ, Sattelle DB. Partridge FA, et al. PLoS Negl Trop Dis. 2018 Jul 11;12(7):e0006487. doi: 10.1371/journal.pntd.0006487. eCollection 2018 Jul. PLoS Negl Trop Dis. 2018. PMID: 29995893 Free PMC article.
Improved reference genome of Aedes aegypti informs arbovirus vector control.
Matthews BJ, Dudchenko O, Kingan SB, Koren S, Antoshechkin I, Crawford JE, Glassford WJ, Herre M, Redmond SN, Rose NH, Weedall GD, Wu Y, Batra SS, Brito-Sierra CA, Buckingham SD, Campbell CL, Chan S, Cox E, Evans BR, Fansiri T, Filipović I, Fontaine A, Gloria-Soria A, Hall R, Joardar VS, Jones AK, Kay RGG, Kodali VK, Lee J, Lycett GJ, Mitchell SN, Muehling J, Murphy MR, Omer AD, Partridge FA, Peluso P, Aiden AP, Ramasamy V, Rašić G, Roy S, Saavedra-Rodriguez K, Sharan S, Sharma A, Smith ML, Turner J, Weakley AM, Zhao Z, Akbari OS, Black WC 4th, Cao H, Darby AC, Hill CA, Johnston JS, Murphy TD, Raikhel AS, Sattelle DB, Sharakhov IV, White BJ, Zhao L, Aiden EL, Mann RS, Lambrechts L, Powell JR, Sharakhova MV, Tu Z, Robertson HM, McBride CS, Hastie AR, Korlach J, Neafsey DE, Phillippy AM, Vosshall LB. Matthews BJ, et al. Among authors: partridge fa. Nature. 2018 Nov;563(7732):501-507. doi: 10.1038/s41586-018-0692-z. Epub 2018 Nov 14. Nature. 2018. PMID: 30429615 Free PMC article.
C. elegans expressing D76N β2-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis.
Faravelli G, Raimondi S, Marchese L, Partridge FA, Soria C, Mangione PP, Canetti D, Perni M, Aprile FA, Zorzoli I, Di Schiavi E, Lomas DA, Bellotti V, Sattelle DB, Giorgetti S. Faravelli G, et al. Among authors: partridge fa. Sci Rep. 2019 Dec 27;9(1):19960. doi: 10.1038/s41598-019-56498-5. Sci Rep. 2019. PMID: 31882874 Free PMC article.
Structural Requirements for Dihydrobenzoxazepinone Anthelmintics: Actions against Medically Important and Model Parasites: Trichuris muris, Brugia malayi, Heligmosomoides polygyrus, and Schistosoma mansoni.
Partridge FA, Bataille CJR, Forman R, Marriott AE, Forde-Thomas J, Häberli C, Dinsdale RL, O'Sullivan JDB, Willis NJ, Wynne GM, Whiteland H, Archer J, Steven A, Keiser J, Turner JD, Hoffmann KF, Taylor MJ, Else KJ, Russell AJ, Sattelle DB. Partridge FA, et al. ACS Infect Dis. 2021 May 14;7(5):1260-1274. doi: 10.1021/acsinfecdis.1c00025. Epub 2021 Apr 2. ACS Infect Dis. 2021. PMID: 33797218 Free PMC article.
17 results