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(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties.
Amata E, Rescifina A, Prezzavento O, Arena E, Dichiara M, Pittalà V, Montilla-García Á, Punzo F, Merino P, Cobos EJ, Marrazzo A. Amata E, et al. Among authors: cobos ej. J Med Chem. 2018 Jan 11;61(1):372-384. doi: 10.1021/acs.jmedchem.7b01584. Epub 2017 Dec 20. J Med Chem. 2018. PMID: 29220177
Potentiation of morphine-induced mechanical antinociception by σ₁ receptor inhibition: role of peripheral σ₁ receptors.
Sánchez-Fernández C, Nieto FR, González-Cano R, Artacho-Cordón A, Romero L, Montilla-García Á, Zamanillo D, Baeyens JM, Entrena JM, Cobos EJ. Sánchez-Fernández C, et al. Among authors: cobos ej. Neuropharmacology. 2013 Jul;70:348-58. doi: 10.1016/j.neuropharm.2013.03.002. Epub 2013 Mar 21. Neuropharmacology. 2013. PMID: 23524304
Modulation of peripheral μ-opioid analgesia by σ1 receptors.
Sánchez-Fernández C, Montilla-García Á, González-Cano R, Nieto FR, Romero L, Artacho-Cordón A, Montes R, Fernández-Pastor B, Merlos M, Baeyens JM, Entrena JM, Cobos EJ. Sánchez-Fernández C, et al. Among authors: cobos ej. J Pharmacol Exp Ther. 2014 Jan;348(1):32-45. doi: 10.1124/jpet.113.208272. Epub 2013 Oct 23. J Pharmacol Exp Ther. 2014. PMID: 24155346
Sigma-1 receptors control immune-driven peripheral opioid analgesia during inflammation in mice.
Tejada MA, Montilla-García A, Cronin SJ, Cikes D, Sánchez-Fernández C, González-Cano R, Ruiz-Cantero MC, Penninger JM, Vela JM, Baeyens JM, Cobos EJ. Tejada MA, et al. Among authors: cobos ej. Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):8396-8401. doi: 10.1073/pnas.1620068114. Epub 2017 Jul 17. Proc Natl Acad Sci U S A. 2017. PMID: 28716934 Free PMC article.
61 results