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Alterations in the in vitro and in vivo regulation of muscle regeneration in healthy ageing and the influence of sarcopenia.
Brzeszczyńska J, Meyer A, McGregor R, Schilb A, Degen S, Tadini V, Johns N, Langen R, Schols A, Glass DJ, Roubenoff R, Ross JA, Fearon KCH, Greig CA, Jacobi C. Brzeszczyńska J, et al. Among authors: jacobi c. J Cachexia Sarcopenia Muscle. 2018 Feb;9(1):93-105. doi: 10.1002/jcsm.12252. Epub 2017 Dec 6. J Cachexia Sarcopenia Muscle. 2018. PMID: 29214748 Free PMC article.
GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration.
Egerman MA, Cadena SM, Gilbert JA, Meyer A, Nelson HN, Swalley SE, Mallozzi C, Jacobi C, Jennings LL, Clay I, Laurent G, Ma S, Brachat S, Lach-Trifilieff E, Shavlakadze T, Trendelenburg AU, Brack AS, Glass DJ. Egerman MA, et al. Among authors: jacobi c. Cell Metab. 2015 Jul 7;22(1):164-74. doi: 10.1016/j.cmet.2015.05.010. Epub 2015 May 19. Cell Metab. 2015. PMID: 26001423 Free PMC article.
Omics/systems biology and cancer cachexia.
Gallagher IJ, Jacobi C, Tardif N, Rooyackers O, Fearon K. Gallagher IJ, et al. Among authors: jacobi c. Semin Cell Dev Biol. 2016 Jun;54:92-103. doi: 10.1016/j.semcdb.2015.12.022. Epub 2016 Jan 16. Semin Cell Dev Biol. 2016. PMID: 26783720 Review.
Loss of oxidative defense and potential blockade of satellite cell maturation in the skeletal muscle of patients with cancer but not in the healthy elderly.
Brzeszczyńska J, Johns N, Schilb A, Degen S, Degen M, Langen R, Schols A, Glass DJ, Roubenoff R, Greig CA, Jacobi C, Fearon KCh, Ross JA. Brzeszczyńska J, et al. Among authors: jacobi c. Aging (Albany NY). 2016 Aug;8(8):1690-702. doi: 10.18632/aging.101006. Aging (Albany NY). 2016. PMID: 27454226 Free PMC article.
Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling.
Pettersen K, Andersen S, Degen S, Tadini V, Grosjean J, Hatakeyama S, Tesfahun AN, Moestue S, Kim J, Nonstad U, Romundstad PR, Skorpen F, Sørhaug S, Amundsen T, Grønberg BH, Strasser F, Stephens N, Hoem D, Molven A, Kaasa S, Fearon K, Jacobi C, Bjørkøy G. Pettersen K, et al. Among authors: jacobi c. Sci Rep. 2017 May 17;7(1):2046. doi: 10.1038/s41598-017-02088-2. Sci Rep. 2017. PMID: 28515477 Free PMC article.
Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy.
Morvan F, Rondeau JM, Zou C, Minetti G, Scheufler C, Scharenberg M, Jacobi C, Brebbia P, Ritter V, Toussaint G, Koelbing C, Leber X, Schilb A, Witte F, Lehmann S, Koch E, Geisse S, Glass DJ, Lach-Trifilieff E. Morvan F, et al. Among authors: jacobi c. Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12448-12453. doi: 10.1073/pnas.1707925114. Epub 2017 Nov 6. Proc Natl Acad Sci U S A. 2017. PMID: 29109273 Free PMC article.
481 results