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Page 1
Ligand-activated BMP signaling inhibits cell differentiation and death to promote melanoma.
Venkatesan AM, Vyas R, Gramann AK, Dresser K, Gujja S, Bhatnagar S, Chhangawala S, Gomes CBF, Xi HS, Lian CG, Houvras Y, Edwards YJK, Deng A, Green M, Ceol CJ. Venkatesan AM, et al. Among authors: chhangawala s. J Clin Invest. 2018 Jan 2;128(1):294-308. doi: 10.1172/JCI92513. Epub 2017 Dec 4. J Clin Invest. 2018. PMID: 29202482 Free PMC article.
RSK1 activation promotes invasion in nodular melanoma.
Salhi A, Farhadian JA, Giles KM, Vega-Saenz de Miera E, Silva IP, Bourque C, Yeh K, Chhangawala S, Wang J, Ye F, Zhang DY, Hernando-Monge E, Houvras Y, Osman I. Salhi A, et al. Among authors: chhangawala s. Am J Pathol. 2015 Mar;185(3):704-16. doi: 10.1016/j.ajpath.2014.11.021. Epub 2015 Jan 8. Am J Pathol. 2015. PMID: 25579842 Free PMC article.
SPOP mutation leads to genomic instability in prostate cancer.
Boysen G, Barbieri CE, Prandi D, Blattner M, Chae SS, Dahija A, Nataraj S, Huang D, Marotz C, Xu L, Huang J, Lecca P, Chhangawala S, Liu D, Zhou P, Sboner A, de Bono JS, Demichelis F, Houvras Y, Rubin MA. Boysen G, et al. Among authors: chhangawala s. Elife. 2015 Sep 16;4:e09207. doi: 10.7554/eLife.09207. Elife. 2015. PMID: 26374986 Free PMC article.
Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth.
Cox AG, Hwang KL, Brown KK, Evason K, Beltz S, Tsomides A, O'Connor K, Galli GG, Yimlamai D, Chhangawala S, Yuan M, Lien EC, Wucherpfennig J, Nissim S, Minami A, Cohen DE, Camargo FD, Asara JM, Houvras Y, Stainier DYR, Goessling W. Cox AG, et al. Among authors: chhangawala s. Nat Cell Biol. 2016 Aug;18(8):886-896. doi: 10.1038/ncb3389. Epub 2016 Jul 18. Nat Cell Biol. 2016. PMID: 27428308 Free PMC article.
Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis.
Cox AG, Tsomides A, Kim AJ, Saunders D, Hwang KL, Evason KJ, Heidel J, Brown KK, Yuan M, Lien EC, Lee BC, Nissim S, Dickinson B, Chhangawala S, Chang CJ, Asara JM, Houvras Y, Gladyshev VN, Goessling W. Cox AG, et al. Among authors: chhangawala s. Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):E5562-71. doi: 10.1073/pnas.1600204113. Epub 2016 Sep 1. Proc Natl Acad Sci U S A. 2016. PMID: 27588899 Free PMC article.
Oncogenic BRAF disrupts thyroid morphogenesis and function via twist expression.
Anelli V, Villefranc JA, Chhangawala S, Martinez-McFaline R, Riva E, Nguyen A, Verma A, Bareja R, Chen Z, Scognamiglio T, Elemento O, Houvras Y. Anelli V, et al. Among authors: chhangawala s. Elife. 2017 Mar 28;6:e20728. doi: 10.7554/eLife.20728. Elife. 2017. PMID: 28350298 Free PMC article.
Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth.
Cox AG, Tsomides A, Yimlamai D, Hwang KL, Miesfeld J, Galli GG, Fowl BH, Fort M, Ma KY, Sullivan MR, Hosios AM, Snay E, Yuan M, Brown KK, Lien EC, Chhangawala S, Steinhauser ML, Asara JM, Houvras Y, Link B, Vander Heiden MG, Camargo FD, Goessling W. Cox AG, et al. Among authors: chhangawala s. EMBO J. 2018 Nov 15;37(22):e100294. doi: 10.15252/embj.2018100294. Epub 2018 Oct 22. EMBO J. 2018. PMID: 30348863 Free PMC article.
Depletion of tet2 results in age-dependent changes in DNA methylation and gene expression in a zebrafish model of myelodysplastic syndrome.
Neelamraju Y, Gjini E, Chhangawala S, Fan H, He S, Jing CB, Nguyen AT, Prajapati S, Sheridan C, Houvras Y, Melnick A, Look AT, Garrett-Bakelman FE. Neelamraju Y, et al. Among authors: chhangawala s. Front Hematol. 2023;2:1235170. doi: 10.3389/frhem.2023.1235170. Epub 2023 Sep 14. Front Hematol. 2023. PMID: 37937078 Free PMC article.
IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation.
Park SM, Cho H, Thornton AM, Barlowe TS, Chou T, Chhangawala S, Fairchild L, Taggart J, Chow A, Schurer A, Gruet A, Witkin MD, Kim JH, Shevach EM, Krivtsov A, Armstrong SA, Leslie C, Kharas MG. Park SM, et al. Among authors: chhangawala s. Cell Stem Cell. 2019 Jan 3;24(1):153-165.e7. doi: 10.1016/j.stem.2018.10.016. Epub 2018 Nov 21. Cell Stem Cell. 2019. PMID: 30472158 Free PMC article.
28 results