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Migratory CD11b+ conventional dendritic cells induce T follicular helper cell-dependent antibody responses.
Krishnaswamy JK, Gowthaman U, Zhang B, Mattsson J, Szeponik L, Liu D, Wu R, White T, Calabro S, Xu L, Collet MA, Yurieva M, Alsén S, Fogelstrand P, Walter A, Heath WR, Mueller SN, Yrlid U, Williams A, Eisenbarth SC. Krishnaswamy JK, et al. Among authors: wu r. Sci Immunol. 2017 Dec 1;2(18):eaam9169. doi: 10.1126/sciimmunol.aam9169. Sci Immunol. 2017. PMID: 29196450 Free PMC article.
Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration.
Krishnaswamy JK, Singh A, Gowthaman U, Wu R, Gorrepati P, Sales Nascimento M, Gallman A, Liu D, Rhebergen AM, Calabro S, Xu L, Ranney P, Srivastava A, Ranson M, Gorham JD, McCaw Z, Kleeberger SR, Heinz LX, Müller AC, Bennett KL, Superti-Furga G, Henao-Mejia J, Sutterwala FS, Williams A, Flavell RA, Eisenbarth SC. Krishnaswamy JK, et al. Among authors: wu r. Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):3056-61. doi: 10.1073/pnas.1501554112. Epub 2015 Feb 23. Proc Natl Acad Sci U S A. 2015. PMID: 25713392 Free PMC article.
Cryptic activation of an Irf8 enhancer governs cDC1 fate specification.
Durai V, Bagadia P, Granja JM, Satpathy AT, Kulkarni DH, Davidson JT 4th, Wu R, Patel SJ, Iwata A, Liu TT, Huang X, Briseño CG, Grajales-Reyes GE, Wöhner M, Tagoh H, Kee BL, Newberry RD, Busslinger M, Chang HY, Murphy TL, Murphy KM. Durai V, et al. Among authors: wu r. Nat Immunol. 2019 Sep;20(9):1161-1173. doi: 10.1038/s41590-019-0450-x. Epub 2019 Aug 12. Nat Immunol. 2019. PMID: 31406378 Free PMC article.
cDC1 prime and are licensed by CD4+ T cells to induce anti-tumour immunity.
Ferris ST, Durai V, Wu R, Theisen DJ, Ward JP, Bern MD, Davidson JT 4th, Bagadia P, Liu T, Briseño CG, Li L, Gillanders WE, Wu GF, Yokoyama WM, Murphy TL, Schreiber RD, Murphy KM. Ferris ST, et al. Among authors: wu gf, wu r. Nature. 2020 Aug;584(7822):624-629. doi: 10.1038/s41586-020-2611-3. Epub 2020 Aug 12. Nature. 2020. PMID: 32788723 Free PMC article.
WDFY4 deficiency in NOD mice ameliorates autoimmune diabetes and insulitis.
Ferris ST, Liu T, Chen J, Ohara RA, Ou F, Wu R, Kim S, Murphy TL, Murphy KM. Ferris ST, et al. Among authors: wu r. Proc Natl Acad Sci U S A. 2023 Mar 28;120(13):e2219956120. doi: 10.1073/pnas.2219956120. Epub 2023 Mar 20. Proc Natl Acad Sci U S A. 2023. PMID: 36940342 Free PMC article.
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