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Page 1
Paving TRAIL's Path with Ubiquitin.
Lafont E, Hartwig T, Walczak H. Lafont E, et al. Among authors: hartwig t. Trends Biochem Sci. 2018 Jan;43(1):44-60. doi: 10.1016/j.tibs.2017.11.002. Epub 2017 Nov 28. Trends Biochem Sci. 2018. PMID: 29195774 Free article. Review.
LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L.
Taraborrelli L, Peltzer N, Montinaro A, Kupka S, Rieser E, Hartwig T, Sarr A, Darding M, Draber P, Haas TL, Akarca A, Marafioti T, Pasparakis M, Bertin J, Gough PJ, Bouillet P, Strasser A, Leverkus M, Silke J, Walczak H. Taraborrelli L, et al. Among authors: hartwig t. Nat Commun. 2018 Sep 25;9(1):3910. doi: 10.1038/s41467-018-06155-8. Nat Commun. 2018. PMID: 30254289 Free PMC article.
TRAIL-receptor 2-a novel negative regulator of p53.
Willms A, Schupp H, Poelker M, Adawy A, Debus JF, Hartwig T, Krichel T, Fritsch J, Singh S, Walczak H, von Karstedt S, Schäfer H, Trauzold A. Willms A, et al. Among authors: hartwig t. Cell Death Dis. 2021 Jul 31;12(8):757. doi: 10.1038/s41419-021-04048-1. Cell Death Dis. 2021. PMID: 34333527 Free PMC article.
Cancer cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion, and metastasis.
von Karstedt S, Conti A, Nobis M, Montinaro A, Hartwig T, Lemke J, Legler K, Annewanter F, Campbell AD, Taraborrelli L, Grosse-Wilde A, Coy JF, El-Bahrawy MA, Bergmann F, Koschny R, Werner J, Ganten TM, Schweiger T, Hoetzenecker K, Kenessey I, Hegedüs B, Bergmann M, Hauser C, Egberts JH, Becker T, Röcken C, Kalthoff H, Trauzold A, Anderson KI, Sansom OJ, Walczak H. von Karstedt S, et al. Among authors: hartwig t. Cancer Cell. 2015 Apr 13;27(4):561-73. doi: 10.1016/j.ccell.2015.02.014. Epub 2015 Apr 2. Cancer Cell. 2015. PMID: 25843002 Free PMC article.
LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes.
Draber P, Kupka S, Reichert M, Draberova H, Lafont E, de Miguel D, Spilgies L, Surinova S, Taraborrelli L, Hartwig T, Rieser E, Martino L, Rittinger K, Walczak H. Draber P, et al. Among authors: hartwig t. Cell Rep. 2015 Dec 15;13(10):2258-72. doi: 10.1016/j.celrep.2015.11.009. Epub 2015 Dec 6. Cell Rep. 2015. PMID: 26670046 Free PMC article.
--LUBAC deficiency perturbs TLR3 signaling to cause immunodeficiency and autoinflammation.
Zinngrebe J, Rieser E, Taraborrelli L, Peltzer N, Hartwig T, Ren H, Kovács I, Endres C, Draber P, Darding M, von Karstedt S, Lemke J, Dome B, Bergmann M, Ferguson BJ, Walczak H. Zinngrebe J, et al. Among authors: hartwig t. J Exp Med. 2016 Nov 14;213(12):2671-2689. doi: 10.1084/jem.20160041. Epub 2016 Oct 24. J Exp Med. 2016. PMID: 27810922 Free PMC article.
LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis.
Peltzer N, Darding M, Montinaro A, Draber P, Draberova H, Kupka S, Rieser E, Fisher A, Hutchinson C, Taraborrelli L, Hartwig T, Lafont E, Haas TL, Shimizu Y, Böiers C, Sarr A, Rickard J, Alvarez-Diaz S, Ashworth MT, Beal A, Enver T, Bertin J, Kaiser W, Strasser A, Silke J, Bouillet P, Walczak H. Peltzer N, et al. Among authors: hartwig t. Nature. 2018 May;557(7703):112-117. doi: 10.1038/s41586-018-0064-8. Epub 2018 Apr 25. Nature. 2018. PMID: 29695863 Free PMC article.
124 results