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A novel, orally active alpha 4 integrin antagonist, AJM300 prevents the development of experimental colitis induced by adoptive transfer of IL-10 deficient CD4(+) T cells in mice.
Sugiura T, Kageyama S, Andou A, Miyazawa T, Ejima C, Nakayama A, Dohi T, Eda H. Sugiura T, et al. Among authors: ejima c. J Pharmacol Exp Ther. 2012 Jul 3. doi: 10.1124/jpet.112.193946. Epub 2012 Jul 3. J Pharmacol Exp Ther. 2012. PMID: 22588256 Retracted. No abstract available.
Interaction Analysis of FABP4 Inhibitors by X-ray Crystallography and Fragment Molecular Orbital Analysis.
Tagami U, Takahashi K, Igarashi S, Ejima C, Yoshida T, Takeshita S, Miyanaga W, Sugiki M, Tokumasu M, Hatanaka T, Kashiwagi T, Ishikawa K, Miyano H, Mizukoshi T. Tagami U, et al. Among authors: ejima c. ACS Med Chem Lett. 2016 Feb 16;7(4):435-9. doi: 10.1021/acsmedchemlett.6b00040. eCollection 2016 Apr 14. ACS Med Chem Lett. 2016. PMID: 27096055 Free PMC article.
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