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Inhibition of Delta-induced Notch signaling using fucose analogs.
Schneider M, Kumar V, Nordstrøm LU, Feng L, Takeuchi H, Hao H, Luca VC, Garcia KC, Stanley P, Wu P, Haltiwanger RS. Schneider M, et al. Among authors: haltiwanger rs. Nat Chem Biol. 2018 Jan;14(1):65-71. doi: 10.1038/nchembio.2520. Epub 2017 Nov 27. Nat Chem Biol. 2018. PMID: 29176671 Free PMC article.
Fringe is a glycosyltransferase that modifies Notch.
Moloney DJ, Panin VM, Johnston SH, Chen J, Shao L, Wilson R, Wang Y, Stanley P, Irvine KD, Haltiwanger RS, Vogt TF. Moloney DJ, et al. Among authors: haltiwanger rs. Nature. 2000 Jul 27;406(6794):369-75. doi: 10.1038/35019000. Nature. 2000. PMID: 10935626
O-fucosylation of notch occurs in the endoplasmic reticulum.
Luo Y, Haltiwanger RS. Luo Y, et al. Among authors: haltiwanger rs. J Biol Chem. 2005 Mar 25;280(12):11289-94. doi: 10.1074/jbc.M414574200. Epub 2005 Jan 14. J Biol Chem. 2005. PMID: 15653671 Free article.
Highly conserved O-fucose sites have distinct effects on Notch1 function.
Rampal R, Arboleda-Velasquez JF, Nita-Lazar A, Kosik KS, Haltiwanger RS. Rampal R, et al. Among authors: haltiwanger rs. J Biol Chem. 2005 Sep 16;280(37):32133-40. doi: 10.1074/jbc.M506104200. Epub 2005 Jul 1. J Biol Chem. 2005. PMID: 15994302 Free PMC article.
152 results